Academic Staff and Fellows
- Mizuki KITAMATSU
- Associate Professor Doctor of Engineering
- Department/Applied Chemistry Graduate school/Molecular and Material Engineering
This laboratory specializes in peptide chemistry and bio-organic chemistry. Our research efforts revolve around creating non-naturally occurring peptides and nucleic acids having new functions that are unavailable in natural peptides/proteins and nucleic acids.
A fragment peptide (B-9(66)) in trasncription factor p53 shows apoptotic activity.
|Research Area||Chemical Biology, Peptide Chemistry|
|Teaching (Graduate Course)||Bio-Structural Materials Chemistry|
|Research Interests||Drug delivery system, Cell-penetrating peptides, Bioactive peptides, Medicinal chemstry, Peptide nucleic acids|
(1) A Leucine Zipper-based Peptide Hybrid Delivers Functional Nanog Protein inside the Cell Nucleus, Bioorganic and Medicinal Chemistry Letters, in press, DOI:10.1016/j.bmcl.2019.02.004
(2) Combined Apoptotic Effects of Peptide and miRNA in a Peptide/miRNA Nanocomplex, Journal of Bioscience and Bioengineering, in press, DOI:10.1016/j.jbiosc.2019.01.003
(3) Selective Growth Inhibition of Porphyromonas Gingivalis and Aggregatibacter Actinomycetemcomitans by Antisense Peptide Nucleic Acids, Molecular and Cellular Probes, Vol.43, pp.45-49(2019), DOI:10.1016/j.mcp.2018.11.006
|Research and Achievements|
Bio-Physical Chemistry Laboratory