Academic Staff and Fellows
- SHIMAMOTO Shigeru
- Lecturer Ph.D. (Pharmacy)
- Department/Life Science Graduate school/Science
The function of proteins depends on its native tertiary structure. In order to clarify their function mechanism and regulate their function, we perform the structure determination of proteins and thermodynamic analysis.
Interaction between Protein and Ligand.
|Research Area||Structural Biology, Thermodynamics|
1）ITC Analysis of Ligand Binding to Lipocalin-type Prostaglandin D Synthase., Netsu Sokutei, 44(3), 108-116 (2017)
2）N-terminal HCV core protein fragment decreases 20S proteasome activity in the presence of PA28γ., Biochem. Biophys. Res. Commun., 509(2), 590-595 (2019)
3）Crystal structure of the dog allergen Can f 6 and structure-based implications of its cross-reactivity with the cat allergen Fel d 4., Sci. Rep., 9(1), 1503 (2019)
Molecular Function and Structure Regulation Laboratory