Academic Staff and Fellows

Associate Professor Ph.D
Department/Science  Graduate school/Science

Biomolecules are nanometer-sized molecular machines working in living cells. Our research goal is to elucidate the operating principle how biological molecular machines work efficiently in collaboration with water molecules.

High-pressure microscopy

Research Area Biophysics, Bioimaging
Selected Publications (1) Nishiyama M., Higuchi H. & Yanagida T. 
Chemomechanical coupling of the forward and backward steps of single kinesin molecules. 
Nature Cell Biology 4, 790-797 (2002).【ISI Times Cited: 244 (2022/01/31)】

(2) Yagi T. & Nishiyama M.
High hydrostatic pressure induces vigorous flagellar beating in Chlamydomonas non-motile mutants lacking the central apparatus.  
Sci Rep. 10(1):2072 (2020). 

Faculty of 1000 Prime (2020/03/06)

(3) Hata H., Nishihara Y., Nishiyama M., Sowa Y., Kawagishi I. & Kitao A. 
High pressure inhibits signaling protein binding to the flagellar motor and bacterial chemotaxis through enhanced hydration.
Sci Rep. 10(1):2351 (2020).
Affiliated Academic Societies Biophysical Society (USA),The Biophysical Society of Japan, The Japan Society for Applied Physics
(Undergraduate Course)
Department of Physics, Faculty of Science, Osaka City University
(Master's/Doctral Course)
Graduate School of Engineering Science, Osaka University
Title of Thesis, Institute, Date Nanometry of the single motor-molecules with high temporal resolution, Osaka University, March 2001
Awards The Young Scientists’ Prize, The Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology

Laboratory for Dynamic Living Systems

E-mail mnishiyama(at)
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Academic Staff and Fellows