Researchers

YONESAKA Kimio

YONESAKA Kimio
Associate Professor
Faculty Department of Medicine / Graduate School of Medical Sciences
Researchmap https://researchmap.jp/mahoy

Research Activities

Research Areas

  • Life sciences, Tumor diagnostics and therapeutics

Research Interests

cancer

Published Papers

  1. Spatial single-cell proteotyping reveals immunotherapy-resistant features within the complex tumor microenvironment of metastatic NSCLC
    Kohsuke Isomoto; Koji Haratani (co-first author and corresponding author); Takahiro Tsujikawa; Shuta Tomida; Yusuke Makutani; Masayuki Takeda; Kimio Yonesaka; Kaoru Tanaka; Tsutomu Iwasa; Kazuko Sakai; Kazuto Nishio; Akihiko Ito; Kazuhiko Nakagawa; Hidetoshi Hayashi
    Journal of Clinical Investigation  10, Mar. 2026  , Refereed
  2. Zongertinib, a Novel HER2 Tyrosine Kinase Inhibitor, Maintains an Anticancer Activity for Trastuzumab Deruxtecan-Resistant Cancers Harboring HER2-Overexpression.
    Takashi Kurosaki; Shinichiro Suzuki; Kimio Yonesaka; Yusuke Kawanaka; Toshiyuki Takehara; Takeshi Teramura; Kazuko Sakai; Kazuto Nishio; Hidetoshi Hayashi
    International journal of molecular sciences  26  (21)  29, Oct. 2025 
  3. 生殖細胞系列BRCA2変異に対するオラパリブの投与により長期奏効を得た原発不明癌の1例
    村岡 未沙子; 稲垣 千晶; 三谷 誠一郎; 高濱 隆幸; 米阪 仁雄; 白石 直樹; 小田 いつき; 西郷 和真; 田村 和朗; 中川 和彦; 林 秀敏
    日本癌治療学会学術集会抄録集  63回  , ICCJ1-3, Oct. 2025 

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MISC

  1. Chromosomal instability leads to EGFR-TKI refractoriness via cGAS-STING activation in EGFR-mutated non-small cell lung cancer , Kimio Yonesaka; Takashi Kurosaki; Junko Tanizaki; Hisato Kawakami; Kaoru Tanaka; Osamu Maenishi; Shiki Takamura; Kazuko Sakai; Yasutaka Chiba; Takeshi Teramura; Hiroki Goto; Eri Otsuka; Hiroaki Okida; Masanori Funabashi; Yuuri Hashimoto; Kenji Hirotani; Yasuki Kamai; Takashi Kagari; Kazuto Nishio; Kazuhiro Kakimi; Hidetoshi Hayashi , CANCER RESEARCH , 85 , 8 , 15, Apr. 2025
  2. 長期生存を得た切除不能食道癌患者における治療後に生じた他臓器癌の検討 , 渡部亮太郎; 三谷誠一郎; 大倉將生; 稲垣千晶; 谷崎潤子; 田中薫; 岩朝勤; 米阪仁雄; 林秀敏 , 日本内科学会雑誌 , 114 , 2025
  3. Overcoming resistance to KRAS inhibitors due to EGFR activation via PTPRR , 金村宙昌; 鈴木慎一郎; 坂井和子; 西尾和人; 中川和彦; 米阪仁雄 , 日本がん分子標的治療学会学術集会プログラム・抄録集 , 28th , 2024

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Awards & Honors

  1. 2018, 日本肺癌学会 篠井河合賞
  2. 2018, 近畿大学医学会賞
  3. 2018, 第22回日本がん分子標的治療学会 優秀演題賞

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Research Grants & Projects

  1. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Exploring mechanism underlying resistance to kras inhibitor , Kindai University
  2. 文部科学省, 基盤研究（Ｃ）, 頭頸部癌におけるセツキシマブ治療の耐性機序の解明
  3. 文部科学省, 基盤研究（C）, HER2陽性乳癌、胃癌におけるheregulinによる抗HER2薬の効果予測