Researchers
- UEDA Takeshi
- Associate Professor
| Faculty | Department of Medicine / Graduate School of Medical Sciences |
|---|---|
| Researchmap | https://researchmap.jp/nutkwfug |
Research Activities
Research Areas
- Life sciences, Pathobiochemistry
- Life sciences, Tumor biology
Research Interests
epigenetics, molecular oncology, signal transduction, genetically engineered mouse
Published Papers
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Deoxycytidine kinase inactivation enhances gemcitabine resistance and sensitizes mitochondrial metabolism interference in pancreatic cancer.
Dash S; Ueda T; Komuro A; Honda M; Sugisawa R; Okada H
Cell Death & Disease 15 (2) , 131-, Feb. 2024 , Refereed -
One-carbon metabolizing enzyme ALDH1L1 influences mitochondrial metabolism through 5-aminoimidazole-4-carboxamide ribonucleotide accumulation and serine depletion, contributing to tumor suppression.
Sasaki M; Yamamoto K; Ueda T; Irokawa H; Takeda K; Sekine R; Itoh F; Tanaka Y; Kuge S; Shibata N
Scientific Reports 13 (1) , 13486-, Aug. 2023 , Refereed -
MBTD1 preserves adult hematopoietic stem cell pool size and function.
Takubo K; Htun PW; Ueda T; Sera Y; Iwasaki M; Koizumi M; Shiroshita K; Kobayashi H; Haraguchi M; Watanuki S; Honda ZI; Yamasaki N; Nakamura-Ishizu A; Arai F; Motoyama N; Hatta T; Natsume T; Suda T; Honda H
Proceedings of the National Academy of Sciences of the United States of America 120 (32) , e2206860120-, Aug. 2023 , Refereed