Researchers
- TAKEDA Tomoya
- Lecturer
Faculty | Department of Pharmacy |
---|---|
Researchmap | https://researchmap.jp/tomoya |
Education and Career
Education
- 2009/04 - 2011/03 , Kobe University, Graduate School of Medicine,
Academic & Professional Experience
- Apr. 2023 - Today , 近畿大学 薬学部 講師
- Apr. 2018 - Mar. 2023 , Kindai University Faculty of Pharmacy 助教
- Apr. 2014 - Mar. 2018 , Kinki University Faculty of Pharmacy Research Associate
Research Activities
Research Areas
- Life sciences, Tumor biology
Research Interests
がん転移, 分子標的薬耐性, 薬物治療学
Published Papers
-
RANK/RANKL axis promotes migration, invasion, and metastasis of osteosarcoma via activating NF-κB pathway.
Tomoya Takeda; Masanobu Tsubaki; Shuji Genno; Kana Tomita; Shozo Nishida
Experimental cell research 436 (2) , 113978-113978, 15, Mar. 2024 -
HER3/Akt/mTOR pathway is a key therapeutic target for the reduction of triple‑negative breast cancer metastasis via the inhibition of CXCR4 expression.
Tomoya Takeda; Masanobu Tsubaki; Shuji Genno; Kenta Tokunaga; Remi Tanaka; Shozo Nishida
International journal of molecular medicine 52 (3) Sep. 2023 -
Statins enhances antitumor effect of oxaliplatin in KRAS-mutated colorectal cancer cells and inhibits oxaliplatin-induced neuropathy.
Masanobu Tsubaki; Tomoya Takeda; Takuya Matsuda; Kana Kishimoto; Honoka Takefuji; Yuzuki Taniwaki; Misa Ueda; Tadafumi Hoshida; Kazufumi Tanabe; Shozo Nishida
Cancer cell international 23 (1) , 73-73, 17, Apr. 2023
Conference Activities & Talks
- Mechanism of tamoxifen acquired resistance via EMT induction by EGFR activation in breast cancer cells , Tomoya Takeda; Masanobu Tsubaki; Remi Tanaka; Koudai Takimoto; Shozo Nishida , The 82th Annual Meeting of the Japanese Cancer Association , 2023
- EGFR 活性化による EMT 誘導を介したタモキシフェン耐性獲得機序 , 武田 朋也; 椿 正寛; 田中 澪美; 滝本 航大; 西田 升三 , 第27回日本がん分子標的治療学会学術集会 , 2023
- AT9283 exhibits antiproliferative effect on BCR-ABL TKI sensitive and resistant CML cells by inhibition of Aurora. , Tomoya Takeda; Masanobu Tsubaki; Takuya Matsuda; Kana Kishimoto; Remi Tanaka; Shozo Nishida , The 81th Annual Meeting of the Japanese Cancer Association , 2022
MISC
- Overexpression of Serum/Glucocorticoid Regulated Kinase 1 is involved with proteasome inhibitor resistance in multiple myeloma , 木村智裕; 椿正寛; 武田朋也; 松田拓弥; 山本裕太; 森井悠介; 森井悠介; 西田升三 , 日本がん分子標的治療学会学術集会プログラム・抄録集 , 25th , 2021
- Myeloma cells-secreted HGF accelerate the bone destruction via increased RANKL expression in bone marrow stromal cells and osteoblasts , 岸本佳奈; 椿正寛; 武田朋也; 松田拓弥; 山本裕太; 森井悠介; 森井悠介; 西田升三 , 日本がん分子標的治療学会学術集会プログラム・抄録集 , 25th , 2021
- Rhosin inhibits tumor metastasis via suppression of Rho/YAP pathway , 椿正寛; 武田朋也; 松田拓弥; 山本裕太; 木村智裕; 森井悠介; 森井悠介; 西田升三 , 日本がん分子標的治療学会学術集会プログラム・抄録集 , 25th , 2021
Patents
- NIK阻害剤 , 西田升三, 椿正寛, 武田朋也 , 特許第6488264号
- 慢性骨髄性白血病の治療用組成物 , 西田 升三, 椿 正寛, 武田 朋也, 西尾 和人, 中山 隆志, 坂井 和子, 駒居 真紀子, 小野 優里, 深松 真衣 , 特許第6267619号
Research Grants & Projects
- 日本学術振興会, 科学研究費助成事業, 骨微小環境に着目したトリプルネガティブ乳癌の骨転移機序の解明及び治療法の開発 , 近畿大学
- 一般財団法人横山臨床薬理研究助成基金, 骨微小環境を標的としたトリプルネガティブ乳癌の骨転移治療薬の開発
- Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Interaction between triple negative breast cancer and bone marrow stromal cells promote bone metastasis. , Kindai University