Researchers

TAKASHIMA Katsuki

TAKASHIMA Katsuki
Lecturer
Faculty Department of Pharmacy
Researchmap https://researchmap.jp/katsuki_takashima

Education and Career

Education

  • 2012/04 - 2016/03 , University of Toyama, Faculty of Engineering,
  • 2016/04 - 2018/03 , University of Toyama, Graduate School of Science and Engineering for Education,
  • 2018/04 - 2020/03 , University of Toyama, Graduate School of Innovative Life Science,

Academic & Professional Experience

  • Apr. 2025 , Kindai University Faculty of Pharmacy Department of Pharmacy 講師
  • Apr. 2020 - Mar. 2025 , Kindai University Faculty of Pharmacy 助教

Research Activities

Research Areas

  • Life sciences, Pharmaceuticals - chemistry and drug development

Research Interests

有機合成化学, 天然物合成, 医薬品化学

Published Papers

  1. Synthesis and biological evaluation of γ-alkylidenebutenolides isolated from Melodorum fruticosum: the role of the propylidene-type side chain structure on anti-melanogenic activity.
    Katsuki Takashima; Yoshiaki Manse; Riko Suzuki; Nanami Masuda; Yuki Fukuda; Risa Fukuda; Shinsuke Marumoto; Fumihiro Ishikawa; Toshio Morikawa; Genzoh Tanabe
    Org. Biomol. Chem.  2025  (23)  , 4497-4507, 14, Apr. 2025  , Refereed
  2. Radical Nitrososulfonation of Propargyl Alcohols: Thiazolidine-2,4-dione-Assisted Synthesis of 5-Alykyl-4-sulfonylisoxazoles
    Tomoki Nakano; Nami Kousaka; Aoi Nakayama; Yoshiaki Kato; Katsuki Takashima; Genzoh Tanabe; Mitsuhiro Yoshimatsu
    Org.Lett.  26  (9)  , 1753-1757, 27, Feb. 2024  , Refereed
  3. Role of the thiosugar ring in the inhibitory activity of salacinol, a potent natural α-glucosidase inhibitor
    Katsuki Takashima; Shinya Nakamura; Maiko Nagayama; Shinsuke Marumoto; Fumihiro Ishikawa; Weijia Xie; Isao Nakanishi; Osamu Muraoka; Toshio Morikawa; Genzoh Tanabe
    RSC Adv.  14  (7)  , 4471-4481, 2024  , Refereed

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Conference Activities & Talks

  1. Synthetic study of geranylated coumarin Kayeassamin A , 西川 陽斗; 高島 克輝; 栗原 郁帆; 寺田 実央; 石川 文洋; 森川 敏生; 田邉 元三 , 第 54 回 複素環化学討論会 , 10, Oct. 2025
  2. Synthesis and Evaluation of Indole S,O-Bisdesmosides with Proliferation-Promoting Activity on HFDPC , 高島 克輝; 鈴木 璃子; 萬瀬 貴昭; 石川 文洋; 森川敏生; 田邉 元三 , 第 54 回 複素環化学討論会 , 9, Oct. 2025
  3. Total Synthesis of Calanthoside, a Potential Hair Growth Stimulant, and Its Preliminary Structure–Activity Relationships , Katsuki Takashima; Riko Suzuki; Yoshiaki Manse; Fumihiro Ishikawa; Toshio Morikawa; Genzoh , 第 53 回構造活性相関シンポジウム , 4, Sep. 2025

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MISC

  1. Xanthene 型天然物の全合成からはじまるWalK活性化剤の創生 , 高島 克輝 , ファルマシア , 61 巻 , 6 号 , 555 , Jun. 2025
  2. Total Synthesis of C19 Diterpene Alkaloid Talatisamine , Katsuki Takashima , Journal of Synthetic Organic Chemistry, Japan , 80 , 7 , 691 , 692 , 1, Jul. 2022
  3. Total synthesis of neokotalanol, a potent ��-glucosidase inhibitor isolated from the Ayurvedic traditional medicine, Salacia by utilizing highly diastereoselective intramolecular cyclization of Sulfide , Katsuki Takashima; yuki Kobayashi; Fumihiro Ishikawa; Shinsuke; Marumoto; Genzoh Tanabe , 第62回天然有機化合物討論会 要旨集 , 601 , 606 , Sep. 2020

Patents

  1. アレルギー性疾患改善用組成物 , 西田升三, 椿正寛, 武田朋也, 田邉元三, 高島克輝, 森川敏生
  2. 自己免疫疾患およびアレルギー性疾患改善組成物 , 西田弁三, 椿正寛, 武田朋也, 田邉元三, 高島克輝, 森川敏生
  3. Pharmaceutical composition for preventing cytokine storm , Nishida, Shozo, Tsubaki, Masanobu, Takeda, Tomoya, Tanabe, Genzoh, Takashima, Katsuki, Morikawa, Toshio

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Awards & Honors

  1. Jul. 2023, Back cover, Chem. Comm.
  2. Oct. 2022, Organic & Biomolecular Chemistry, Outside front cover
  3. Feb. 2021, Chemical Pharmaceutical Bulletin, Featured Article

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Research Grants & Projects

  1. 公益財団法人 コーセーコスメトロジー研究財団, コスメトロジー研究助成, 生薬由来の天然物を基盤とする安全かつ強力な育毛成分の開発研究
  2. 近畿大学, 奨励研究助成金, 植物由来ゲラニル型クマリン類の網羅的全合成とその応用
  3. 公益財団法人 持田記念医学薬学振興財団, 2021年度研究助成, 新規AGA治療薬の開発を目指した希少天然物の構造活性相関研究

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