Researchers

SUGIURA Reiko
Professor/Manager
Faculty Department of Pharmaceutical Sciences / Graduate School of Medicine / Pharmaceutical Research and Technology Institute
Researchmap https://researchmap.jp/read0052052

Education and Career

Academic & Professional Experience

  • Oct. 2020 - Today , 近畿大学大学院 薬学研究科長
  • Apr. 2004 - Today , Kindai University Faculty of Pharmacy 教授
  • Oct. 2012 - Sep. 2020 , Kindai University Faculty of Pharmacy, Department of Pharmaceutical Sciences 科長

Research Activities

Research Areas

  • Life sciences, Pharmaceuticals - health and biochemistry
  • Life sciences, Cell biology
  • Life sciences, Pharmacology
  • Life sciences, Applied molecular and cellular biology
  • Life sciences, Pharmacology

Research Interests

Disordered protein, ストレス応答, 細胞死, ゲノム薬理学, ケミカルバイオロジー, 液ー液相分離, ストレス顆粒, カルシニューリン, 分裂酵母, 免疫制御, MAPキナーゼ, 細胞内輸送, RNA結合タンパク質, 分子遺伝学, タンパク質リン酸化, シグナル伝達, RNAバイオロジー, 転写制御, モデル生物, ゲノム創薬

Published Papers

  1. ACAGT-007a, an ERK MAPK Signaling Modulator, in Combination with AKT Signaling Inhibition Induces Apoptosis in KRAS Mutant Pancreatic Cancer T3M4 and MIA-Pa-Ca-2 Cells.
    Golam Iftakhar Khandakar; Ryosuke Satoh; Teruaki Takasaki; Kana Fujitani; Genzoh Tanabe; Kazuko Sakai; Kazuto Nishio; Reiko Sugiura
    Cells  11  (4)  17, Feb. 2022 
  2. Comprehensive Analysis of Prognostic Microenvironment-Related Genes in Invasive Breast Cancer
    Yingrong Shi; Si Chen; Huijuan Xing; Guanglie Jiang; Nan Wu; Qiannan Liu; Norihiro Sakamoto; Takayoshi Kuno; Reiko Sugiura; Qinghuan Xiao; Feng Jin; Yue Fang; Fan Yao
    Frontiers in Oncology  11  , 576911-, 3, Jan. 2022  , Refereed
  3. Ellagic Acid Combined with Tacrolimus Showed Synergistic Cell Growth Inhibition in Fission Yeast.
    Kanako Hagihara; Kousuke Hosonaka; Shuhei Hoshino; Kazuki Iwata; Naoki Ogawa; Ryosuke Satoh; Teruaki Takasaki; Takuya Maeda; Reiko Sugiura
    Biocontrol science  27  (1)  , 31-39, 2022 

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Books etc

  1. 図解腫瘍薬学 , 川西, 正祐; 賀川, 義之; 大井, 一弥 , がん特異的シグナル伝達 , がん特異的シグナル伝達 , 南山堂 , Jul. 2020
  2. 酵母の生命科学と生物工学 : 産業応用から基礎科学へ (DOJIN BIOSCIENCE SERIES) , 原島 俊; 高木 博史 , 化学同人 , 7, Aug. 2013
  3. 岩波 生物学辞典 第5版 , 巌佐 庸; 倉谷 滋; 斎藤 成也; 塚谷 裕一 , 岩波書店 , 27, Feb. 2013

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Conference Activities & Talks

  1. The mechanism of alfa-Synuclein aggregation and toxicity revealed by the fission yeast model system: The role of calcineurin signaling and its relevance to Parkinson's disease , Reiko Sugiura , 第44回日本分子生物学年会 , 3, Dec. 2021
  2. Chemical genetic screen for medicines targeting the aggregation and cytotoxicity of α-synuclein using a fission yeast model of Parki , Yoshitaka Sugimoto; Teruaki Takasaki; Ryo Kurosaki; Yuto Tarui; Yuji Tatsumi; Ryosuke Sato; Reiko Sugiura , 第44回日本分子生物学年会
  3. Mechanism of a novel anticancer compound ACA-28 to regulate ERK MAPK signaling in relation to the nuclear export system , Daiki Fujiwara; Teruaki Takasaki; Naofumi Tomimoto; Takamasa Toyoda, Golam; Khandakar; Ryosuke Satoh; Masahiro Oka; Yoshihiro Yoneda; Reiko Sugiura , 第44回日本分子生物学年会

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MISC

  1. , Ryosuke Satoh; Reiko Sugiura , The CELL , 51 , 12 , 53 , 55 , Sep. 2019
  2. , Ryosuke Satoh; Reiko Sugiura , Precision Medicine , 2 , 6 , 59 , 62 , Jun. 2019
  3. , 佐藤 亮介; 杉浦 麗子 , 生体の科学 , 69 , 4 , 2018

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Patents

  1. 抗腫瘍剤 , 杉浦 麗子, 村岡 修, 筒井 望, 喜多 綾子, 久能 樹 , 特許第6047309号
  2. キャビコール類縁体化合物およびMAPキナーゼシグナル伝達阻害薬 , 杉浦 麗子, 萬瀬 貴昭, 村岡 修, 吉川 雅之, 安原 智久 , 特許第5774049号
  3. 容器の栓体 , 石渡 俊二, 多賀 淳, 藤田 秀樹, 西田 升三, 喜多 綾子, 杉浦 麗子 , 特許第5716064号

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Awards & Honors

  1. Jun. 2018, 神戸大学, 優秀研究者賞
  2. Mar. 2004, 上原記念生命科学振興財団, 上原記念生命科学振興財団 研究奨励賞
  3. 2001, 日本薬理学会学術奨励賞

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Research Grants & Projects

  1. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Mechanisms of cancer-specific apoptosis induction targeting ERK hyperactivation , Kindai University
  2. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Regulatory mechanisms of MAPK signaling and its application to chemicalgenomics , Kinki University
  3. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Comprehensive promotion of research on RNA program

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