Researchers

SHIMAMOTO Shigeru

SHIMAMOTO Shigeru
Associate Professor
Faculty Department of Life Science / Graduate School of Science and Engineering
Researchmap https://researchmap.jp/sshimamoto

Education and Career

Education

  • 2001/04 - 2005/03 , Osaka University, School of Pharmaceutical Sciences,
  • 2005/04 - 2007/03 , 大阪大学大学院, 薬学研究科（博士前期課程）,
  • 2007/04 - 2010/03 , 大阪大学大学院, 薬学研究科（博士後期課程）,

Academic & Professional Experience

  • Apr. 2015 - Today , Kindai University Faculty of Science and Engineering, Department of Life Science 講師
  • Apr. 2011 - Mar. 2014 , Kindai University Faculty of Science and Engineering, Department of Life Science 助教
  • Apr. 2010 - Mar. 2011 , 大阪大学大学院 薬学研究科 日本学術振興会特別研究員(PD)

Research Activities

Research Areas

  • Life sciences, Biophysics
  • Life sciences, Structural biochemistry
  • Nanotechnology/Materials, Molecular biochemistry
  • Life sciences, Pharmaceuticals - analytical and physicochemistry

Research Interests

Biophysical chemistry, protein technology, thermodynamics, structural biology, ITC, NMR, interaction analysis, protein folding, lipocalin, prostaglandin, Lipocalin-type prostaglandin D synthase, 造血器型プロスタグランジンD合成酵素, bioactive peptide, Heat-stable enterotoxin, proprotein, Prouroguanylin

Published Papers

  1. Structural and Catalytic Roles of the Disulfide Bonds Cys19–Cys154 and Cys134–Cys199 in Trypsin-like Proteases: Evolutionary Insights for Disulfide Bond Acquisition
    Maiko Minakata; Yuri Murakami; Orika Ashida; Miki Matsuzaki; Kairi Ogawa; Nanako Saeki; Shigeru Shimamoto; Mitsuhiro Miyazawa; Yuji Hidaka; Nana Sakata
    Molecules  31  (2)  , 351-351, 19, Jan. 2026 
  2. Synthesis and Cancer Cell Targeting of a Boron-Modified Heat-Stable Enterotoxin Analog for Boron Neutron Capture Therapy (BNCT)
    Sota Okazaki; Yoshihide Hattori; Nana Sakata; Masaya Goto; Sarino Kitayama; Hiroko Ikeda; Toshiki Takei; Shigeru Shimamoto; Yuji Hidaka
    Chemistry  7  (4)  , 111-111, 30, Jun. 2025 
  3. Seasonal variations in airborne fungal communities and their ice-nucleation activities at forest environment
    Yukino Tamiya; Shigeru Shimamoto; Sakura Inoue; Teruya Maki
    AEROSOL SCIENCE AND TECHNOLOGY  20, Jun. 2025 

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Books etc

  1. 熱量測定・熱分析ハンドブック , 日本熱測定学会 , タンパク質と低分子の結合（ITC）ー生理活性物質ー , タンパク質と低分子の結合（ITC）ー生理活性物質ー , 丸善 , Aug. 2020
  2. Essential food chemistry , 島本, 茂; 他; 中村, 宜督; 榊原, 啓之; 室田, 佳恵子 , 第五章 アミノ酸とタンパク質 , 第五章 アミノ酸とタンパク質 , 講談社 , Dec. 2018

MISC

  1. 肺癌標的ペプチド付加輸送タンパク質を用いた難水溶性抗癌剤paclitaxelに対するドラッグデリバリーシステム , 高田彩加; 富堯; 古田航祐; 島本茂; 乾隆 , 日本DDS学会学術集会プログラム予稿集 , 39th , 2023
  2. Analyses of the Folding of a Cassette Mutant of Human and Eel Prouroguanylin in a Study of the Role of an Intra-Molecular Chaperone Function on Molecular Evolution , OSUMI Toi; FUKUTSUJI Mayu; MIZOE Koki; SHINTO Ryota; SHIMAMOTO Shigeru; HIDAKA Yuji , Peptide Science , 2020 , 2021
  3. Enzymatic Activities of Recombinant Cocoonase’s in which the Active Site Is Mutated , OGATA Ayumi; TAKEGAWA Mai; MIYAZAWA Mitsuhiro; SHIMAMOTO Shigeru; HIDAKA Yuji , Peptide Science , 2020 , 2021

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Research Grants & Projects

  1. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Molecular Mechanism Underlying the Potentiation of Sleep Induction by L-PGDS , Kindai University
  2. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Nobel ice-nuclei proteins isolated from the metagenomic DNA in bioaerosols , Kindai University
  3. Neopharma Japan, Study of the Antiviral Effects of 5-ALA , Kindai University

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