Researchers

SHIMAMOTO Shigeru

SHIMAMOTO Shigeru
Associate Professor
Faculty Department of Life Science / Graduate School of Science and Engineering
Researchmap https://researchmap.jp/sshimamoto

Education and Career

Education

  • 2001/04 - 2005/03 , Osaka University, School of Pharmaceutical Sciences,
  • 2005/04 - 2007/03 , 大阪大学大学院, 薬学研究科（博士前期課程）,
  • 2007/04 - 2010/03 , 大阪大学大学院, 薬学研究科（博士後期課程）,

Academic & Professional Experience

  • Apr. 2015 - Today , Kindai University Faculty of Science and Engineering, Department of Life Science 講師
  • Apr. 2011 - Mar. 2014 , Kindai University Faculty of Science and Engineering, Department of Life Science 助教
  • Apr. 2010 - Mar. 2011 , 大阪大学大学院 薬学研究科 日本学術振興会特別研究員(PD)

Research Activities

Research Areas

  • Life sciences, Biophysics
  • Life sciences, Structural biochemistry
  • Nanotechnology/Materials, Molecular biochemistry
  • Life sciences, Pharmaceuticals - analytical and physicochemistry

Research Interests

Biophysical chemistry, protein technology, thermodynamics, structural biology, ITC, NMR, interaction analysis, protein folding, lipocalin, prostaglandin, Lipocalin-type prostaglandin D synthase, 造血器型プロスタグランジンD合成酵素, bioactive peptide, Heat-stable enterotoxin, proprotein, Prouroguanylin

Published Papers

  1. A Novel Peptide Reagent for Investigating Disulfide-Coupled Folding Intermediates of Mid-Size Proteins
    Nana Sakata; Yuri Murakami; Mitsuhiro Miyazawa; Shigeru Shimamoto; Yuji Hidaka
    Molecules  28  (8)  , 3494-3504, Apr. 2023  , Refereed
  2. The molecular basis of heat-stable enterotoxin for vaccine development and cancer cell detection
    Masaya Goto; Shinya Yoshino; Kyona Hiroshima; Toru Kawakami; Kaeko Murota; Shigeru Shimamoto; Yuji Hidaka
    Molecules  28  (1)  , 1128-1142, Jan. 2023  , Refereed
  3. Degradation-suppressed cocoonase for investigating the pro-peptide-mediated activation mechanism
    Nana Sakata; Ayumi Ogata; Mai Takegawa; Yuri Murakami; Misaki Nishimura; Mitsuhiro Miyazawa; Teruki Hagiwara; Shigeru Shimamoto; Yuji Hidaka
    Molecules  27  (2)  , 1-13, 20, Nov. 2022  , Refereed

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Books etc

  1. 熱量測定・熱分析ハンドブック , 日本熱測定学会 , タンパク質と低分子の結合（ITC）ー生理活性物質ー , タンパク質と低分子の結合（ITC）ー生理活性物質ー , 丸善 , Aug. 2020
  2. Essential food chemistry , 島本, 茂; 他; 中村, 宜督; 榊原, 啓之; 室田, 佳恵子 , 第五章 アミノ酸とタンパク質 , 第五章 アミノ酸とタンパク質 , 講談社 , Dec. 2018

MISC

  1. Analyses of the Folding of a Cassette Mutant of Human and Eel Prouroguanylin in a Study of the Role of an Intra-Molecular Chaperone Function on Molecular Evolution , OSUMI Toi; FUKUTSUJI Mayu; MIZOE Koki; SHINTO Ryota; SHIMAMOTO Shigeru; HIDAKA Yuji , Peptide Science , 2020 , 2021
  2. Enzymatic Activities of Recombinant Cocoonase’s in which the Active Site Is Mutated , OGATA Ayumi; TAKEGAWA Mai; MIYAZAWA Mitsuhiro; SHIMAMOTO Shigeru; HIDAKA Yuji , Peptide Science , 2020 , 2021
  3. Structural Analyses of the N-terminal Extracellular Domain of the Amyloid Precursor Protein , HANAGAKI Yusaku; KANEMURA Shingo; OKUMURA Masaki; YAMAGUCHI Hiroshi; SHIMAMOTO Shigeru; HIDAKA Yuji , Peptide Science , 2020 , 2021

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Research Grants & Projects

  1. Neopharma Japan, Study of the Antiviral Effects of 5-ALA , Kindai University
  2. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (A), Interaction between brain function and inflammation mediated by prostaglandin D2
  3. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B), substrate-induced product-release mechanism of L-PGDS , Kindai University

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