Researchers

SATOH Ryosuke

SATOH Ryosuke
Lecturer
Faculty Department of Pharmaceutical Sciences
Researchmap https://researchmap.jp/recobagachapin

Education and Career

Academic & Professional Experience

  • Sep. 2023 - Today , McGill University Faculty of Medicine and Health Sciences Visiting Professor
  • Apr. 2019 - Today , Kindai University Department of Pharmaceutical Sciences, Faculty of Pharmacy Lecuturer
  • Apr. 2014 - Mar. 2019 , Kindai University Department of Pharmaceutical Sciences, Faculty of Pharmacy Assistant Professor
  • Apr. 2012 - Mar. 2014 , Microbial Chemistry Research Foundation 基盤生物研究部 Postdoctoral fellow
  • Apr. 2010 - Mar. 2012 , Japan Society for the Promotion of Science(JSPS) Research Fellowship for Young Scientists(DC2)

Research Activities

Research Areas

  • Life sciences, Genetics
  • Nanotechnology/Materials, Chemical biology
  • Life sciences, Pharmaceuticals - health and biochemistry
  • Life sciences, Cell biology
  • Life sciences, Molecular biology

Research Interests

Liquid-liquid phase separation, Phase separation, Phosphorylation, Stress granule, Stress response, Cancer, Fission yeast, Chemical biology, RNA-binding protein, RNA, Signal transduction

Published Papers

  1. Atg1, a key regulator of autophagy, functions to promote MAPK activation and cell death upon calcium overload in fission yeast.
    Teruaki Takasaki; Ryosuke Utsumi; Erika Shimada; Asuka Bamba; Kanako Hagihara; Ryosuke Satoh; Reiko Sugiura
    Microbial cell (Graz, Austria)  10  (6)  , 133-140, 5, Jun. 2023 
  2. ACAGT-007a, an anti-cancer compound that modulates ERK MAPK signaling, induces nuclear enrichment of phosphorylated ERK in T3M4 pancreatic cancer cells.
    Golam Iftakhar Khandakar; Yoichi Miyamoto; Ryosuke Satoh; Kenta Kishimoto; Mingzuo Xie; Mengyu Shih; Teruaki Takasaki; Genzoh Tanabe; Masahiro Oka; Reiko Sugiura
    Genes to cells : devoted to molecular & cellular mechanisms  21, Mar. 2023 
  3. Fission Yeast PUF Proteins Puf3 and Puf4 Are Novel Regulators of PI4P5K Signaling
    Ryosuke Satoh; Taemi Tanaka; Nobuyasu Yoshida; Chiaki Tanaka; Teruaki Takasaki; Reiko Sugiura
    Biological and Pharmaceutical Bulletin  46  (2)  , 163-169, Feb. 2023  , Refereed

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Conference Activities & Talks

  1. ERK: A DOUBLE-EDGED SWORD IN CANCER. ERK-Dependent Apoptosis as a Potential Therapeutic Strategy for Cancer , Teruaki Takasaki; Golam Iftakhar Khandakar; Sae Kamiyama; Ryosuke Satoh; Reiko Sugiura , The Protein Phosphatases Conference Jointly hosted by FASEB and the Japanese Association for Protein Phosphatase Research (JAPPR) , 14, Dec. 2022
  2. FISSION YEAST PUF PROTEINS PUF3 AND PUF4 ARE NOVEL REGULATORS OF PI4P5K SIGNALING , Ryosuke Satoh; Taemi Tanaka; Nobuyasu Yoshida; Teruaki Takasaki; Reiko Sugiura , The Protein Phosphatases Conference Jointly hosted by FASEB and the Japanese Association for Protein Phosphatase Research (JAPPR) , 13, Dec. 2022
  3. ACAGT-007a, A NEW ERK MAPK SIGNALING MODULATOR, WHEN COMBINED WITH AKT SIGNALING INHIBITOR, INHIBITS CELL GROWTH AND TRIGGERS APOPTOSIS IN PANCREATIC CANCER CELLS , Golam Iftakhar Khandakar; Ryosuke Satoh; Teruaki Takasaki; Kana Fujitani; Shih Mengyu; Genzoh Tanabe; Kazuko Sakai; Kazuto Nishio; Yoichi Miyamoto; Masahiro Oka; Reiko Sugiura , The Protein Phosphatases Conference Jointly hosted by FASEB and the Japanese Association for Protein Phosphatase Research (JAPPR) , 13, Dec. 2022

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MISC

  1. Pck2のストレス顆粒局在化を介したPmk1 MAPK経路のネガティブフィードバック機構—Negative feedback regulation of the Pmk1 MAPK pathway through the sequestration of Pck2 into stress granules , 佐藤 亮介; 杉浦 麗子 , 細胞 , 54 , 8 , 466 , 469 , Jul. 2022
  2. Phase separation orchestrates MAP kinase signaling -Stress granules as a promising target for cancer therapy , Ryosuke Satoh; Reiko Sugiura , Seikagaku , 94 , 4 , 557 , 565 , Jul. 2022
  3. PKC/Pck2がストレス顆粒へ移行するメカニズムとPKC/MAPKシグナルの負のフィードバック機構の解析 , 冨本 尚史; 神田 勇輝; 佐藤 亮介; 高崎 輝恒; 杉浦 麗子 , 日本薬学会年会要旨集 , 142年会 , 27J , pm02S , Mar. 2022

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Patents

  1. キャピラリー電気泳動による核酸−タンパク質結合解析法 , 杉浦 麗子, 多賀 淳, 石渡 俊二, 佐藤 亮介
  2. アポトーシス誘導剤と癌治療剤 , 杉浦 麗子, 高崎 輝恒, 佐藤 亮介, 村岡 修, 田邉 元三

Awards & Honors

  1. Sep. 2019, 酵母遺伝学フォーラム, 会長賞
  2. Jan. 2018, 日本薬学会近畿支部, 平成29年度 日本薬学会近畿支部奨励賞

Research Grants & Projects

  1. 日本学術振興会, 科学研究費助成事業 基盤研究(C), RNA相分離によるシグナル伝達スイッチを介した細胞運命制御機構 , 近畿大学
  2. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), RNA顆粒ダイナミクスの制御機構解明と難治性疾患治療への応用 , Kindai University
  3. 近畿大学, 令和3年度学内研究助成金(奨励研究助成金), RNA相分離によって制御されるシグナル伝達スイッチ機構の解明 , 近畿大学

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