Researchers
- SAKAI Kazuko
- Associate Professor
| Faculty | Department of Medicine |
|---|---|
| Researchmap | https://researchmap.jp/wako02 |
Education and Career
Academic & Professional Experience
- 2012 , Kindai University Faculty of Medicine 助教
Research Activities
Research Areas
- Life sciences, Tumor diagnostics and therapeutics
Published Papers
-
Spatial single-cell proteotyping reveals immunotherapy-resistant features within the complex tumor microenvironment of metastatic NSCLC
Kohsuke Isomoto; Koji Haratani (co-first author and corresponding author); Takahiro Tsujikawa; Shuta Tomida; Yusuke Makutani; Masayuki Takeda; Kimio Yonesaka; Kaoru Tanaka; Tsutomu Iwasa; Kazuko Sakai; Kazuto Nishio; Akihiko Ito; Kazuhiko Nakagawa; Hidetoshi Hayashi
Journal of Clinical Investigation 10, Mar. 2026 , Refereed -
Clonal Complexity Defines Distinct Tumor‐Intrinsic Biology and Prognosis in Diffuse Large B‐Cell Lymphoma
Takahiro Haeno; Kazuko Sakai; Shuji Minamoto; Daiki Nakatsu; Marco A. De Velasco; Shinya Rai; Hirokazu Tanaka; Itaru Matsumura; Kazuto Nishio
Cancer Medicine 15 (2) 2, Feb. 2026 -
A case of endometrioid carcinoma of the endometrium that progressed to lethal neuroendocrine carcinoma as a result of TMEM178B-BRAF fusion.
Yoko Kashima; Hisamitu Takaya; Chiho Miyagawa; Tomoyuki Otani; Kazuko Sakai; Kazuto Nishio; Noriomi Matsumura
International cancer conference journal 15 (1) , 99-102, Jan. 2026
Conference Activities & Talks
- 非小細胞肺癌患者における血小板遺伝子発現の腫瘍環境の影響とMRDモニタリングへの応用 , 西尾 和人; 坂井 和子; 小原 秀太; 須田 健一; 津谷 康大; 光冨 徹哉 , 肺癌 , Dec. 2024
- 肺癌におけるRWDの活用 アファチニブからオシメルチニブへの逐次投与を評価する前向き観察研究 Gio-Tag Japan , 角 俊行; 秦 明登; 吉岡 弘鎮; 藤阪 保仁; 守田 亮; 大杉 純; 三井 匡史; 太田 登博; 森田 智視; 坂井 和子; 西尾 和人; 片上 信之 , 肺癌 , Oct. 2024
- EGFR変異陽性非小細胞肺癌患者に対するアファチニブ±ベバシズマブ療法のバイオマーカー探索 , 二宮 貴一朗; 坂井 和子; 大橋 圭明; 石川 暢久; 上月 稔幸; 久山 彰一; 金地 伸拓; 横山 俊秀; 二宮 崇; 堀田 勝幸; 西尾 和人; 木浦 勝行 , 肺癌 , Oct. 2024
MISC
- Discovery of an anticancer seed targeting cancer stem cells and analysis of its mode of action , Miyuki Matsui; Hiroaki Ikeda; Kazuko Sakai; Kazuto Nishio; Masaya Imoto; Hideaki Kakeya , MOLECULAR CANCER THERAPEUTICS , 24 , 10 , B38 , B38 , 22, Oct. 2025
- Chromosomal instability leads to EGFR-TKI refractoriness via cGAS-STING activation in EGFR-mutated non-small cell lung cancer , Kimio Yonesaka; Takashi Kurosaki; Junko Tanizaki; Hisato Kawakami; Kaoru Tanaka; Osamu Maenishi; Shiki Takamura; Kazuko Sakai; Yasutaka Chiba; Takeshi Teramura; Hiroki Goto; Eri Otsuka; Hiroaki Okida; Masanori Funabashi; Yuuri Hashimoto; Kenji Hirotani; Yasuki Kamai; Takashi Kagari; Kazuto Nishio; Kazuhiro Kakimi; Hidetoshi Hayashi , CANCER RESEARCH , 85 , 8 , 15, Apr. 2025
- Pilot Study to Evaluate the Potential of the Tumor Educated Platelets (TEP) as the Tool to Detect Minimal Residual Disease and Drug Resistance , Shuta Ohara; Kenichi Suda; Kazuko Sakai; Junko Tanaka; Takamichi Muramatsu; Chihiro Uematsu; Yasuhiro Tsutani; Kazuto Nishio; Tetsuya Mitsudomi , JOURNAL OF THORACIC ONCOLOGY , 20 , 4 , S6 , S6 , Apr. 2025
Research Grants & Projects
- Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Evaluation of minimal residual disease in postoperative lung cancer using platelet RNA influenced by the tumor environment. , Kindai University
- 日本学術振興会, 科学研究費助成事業, 血中遊離核酸検査の質保証と技能試験の開発；精確な結果に基づくゲノム医療をめざして , 浜松医科大学
- 日本学術振興会, 科学研究費助成事業, 血中遊離核酸検査の質保証と技能試験の開発；精確な結果に基づくゲノム医療をめざして , 浜松医科大学