Researchers

SAITO Takamune

SAITO Takamune
Associate Professor
Faculty Department of Genetic Engineering
Researchmap https://researchmap.jp/takamune.t.saito

Education and Career

Education

  • 1997/04 - 2001/03 , Kindai University, Faculty of Biology-Oriented Science and Technology,
  • 2001/04 - 2003/03 , Osaka University, Graduate School of Science,
  • 2003/04 - 2006/03 , Osaka University, Graduate School of Science,

Academic & Professional Experience

  • Apr. 2018 - Today , Kindai University Faculty of Biology-Oriented Science and Technology, Department of Genetic Engineering Lecturer
  • Jun. 2015 - Mar. 2018 , Harvard Medical School Department of Genetics Research Associate
  • Apr. 2015 - Mar. 2016 , Kindai University Institute of Advanced Technology Researcher
  • Aug. 2014 - Mar. 2015 , Tohoku University Institute of Development, Aging and Cancer Research Assistant Professor
  • Apr. 2006 - Jul. 2014 , Harvard Medical School Department of Genetics Research Fellow
  • Apr. 2007 - Mar. 2009 , Postdoctral Fellowship for Research Abroad Harvard Medical School
  • Apr. 2006 - Mar. 2007 , JSPS research fellow (PD) Harvard Medical School
  • Apr. 2005 - Mar. 2006 , JSPS research fellow (DC2) Osaka University

Research Activities

Research Areas

  • Life sciences, Genetics
  • Life sciences, Molecular biology
  • Life sciences, Cell biology
  • Life sciences, Genomics
  • Life sciences, Evolutionary biology
  • Life sciences, Developmental biology
  • Life sciences, Tumor biology

Research Interests

meiosis, meiotic recombination, Crossover control, Holliday junction, Holliday junction resolvase, structure specific endonuclease, Homologous recombination, Genomic instability, Progeroid syndromes, Bloom syndrome, Xeroderma pigmentosum, Fanconi anemia, DNA repair, Chromosome dynamics, Genomic integrity, mitosis, RNAi, P granule

Published Papers

  1. GRAS-1 is a novel regulator of early meiotic chromosome dynamics in C. elegans
    Marina Martinez-Garcia; Pedro Robles Naharro; Marnie W. Skinner; Kerstin A. Baran; Laura I. Lascarez-Lagunas; Saravanapriah Nadarajan; Nara Shin; Carlos G. Silva-García; Takamune T. Saito; Sara Beese-Sims; Brianna N. Diaz-Pacheco; Elizaveta Berson; Ana B. Castañer; Sarai Pacheco; Enrique Martinez-Perez; Philip W. Jordan; Monica P. Colaiácovo
    PLOS Genetics  19  (2)  , e1010666-e1010666, 21, Feb. 2023  , Refereed
  2. HIM-17 regulates the position of recombination events and GSP-1/2 localization to establish short arm identity on bivalents in meiosis
    Saravanapriah Nadarajan; Elisabeth Altendorfer; Takamune T. Saito; Marina Martinez-Garcia; Monica P. Colaiácovo
    Proceedings of the National Academy of Sciences  118  (17)  , e2016363118-e2016363118, 27, Apr. 2021  , Refereed
  3. The demethylase NMAD-1 regulates DNA replication and repair in the Caenorhabditis elegans germline.
    Simon Yuan Wang; Hui Mao; Hiroki Shibuya; Satoru Uzawa; Zach Klapholz O'Brown; Sage Wesenberg; Nara Shin; Takamune T Saito; Jinmin Gao; Barbara J Meyer; Monica P Colaiácovo; Eric Lieberman Greer
    PLoS genetics  15  (7)  , e1008252-, Jul. 2019  , Refereed

MORE

Conference Activities & Talks

  1. Roles of structure specific endonucleases in larval development and meiosis , Koki Yamamoto; Takamune T. Saito , Kansai Worm Meeting , 8, Jan. 2023
  2. Relationship between unpaired chromosomes and crossover formation , Taiki Tsujiue; Takamune T. Saito , Kansai Aera Worm Meeting , 8, Jan. 2023
  3. Unpaired homologous chromosomes leads novel regulatory mechanisms of crossover formation in C. elegant meiosis. , Koki Yamamoto; Takamune T. Saito , 40th chromosome workshop , 21, Dec. 2022

MORE

MISC

  1. 相同染色体間のギャップ形成が多様性を生む？ , 齋藤貴宗 , 実験医学 , 40 , 8 , 1276 , 1277 , May. 2022
  2. 線虫の染色体対合異常による新規な交差形成制御機構 , 山本航暉; 南寛仁; 齋藤貴宗 , 日本遺伝学会大会プログラム・予稿集 , 94th (CD-ROM) , 2022
  3. Switching of autosomal crossover formations by unpaired sex chromosomes in C. elegans oocytes , 南寛仁; 齋藤貴宗 , 日本分子生物学会年会プログラム・要旨集(Web) , 44th , 2021

MORE

Awards & Honors

  1. Dec. 2013, The Molecular Biology Society of Japan, The invitation plan for postdoctoral fellows from overseas
  2. May. 2011, Genetics Society of America, DeLill Nasser Awards
  3. Sep. 2010, Harvard Medical School, Postdoctoral Travel Awards

MORE

Research Grants & Projects

  1. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Regulatory mechanisms of multinuclease complex , Kindai University
  2. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Novel machinery of maintenance of genomic integrity by multinuclease complexes , Kindai University
  3. Ministry of Education, Culture, Sports, Science and Technology, Grant-in-Aid for Young Scientists (B), Tissue-specific maintenance of genomic integrity by multinuclease complexes , 東北大学

MORE