Researchers

SAITO Takamune

SAITO Takamune
Lecturer
Faculty Department of Genetic Engineering
Researchmap https://researchmap.jp/takamune.t.saito

Education and Career

Education

  • 1997/04 - 2001/03 , Kindai University, Faculty of Biology-Oriented Science and Technology,
  • 2001/04 - 2003/03 , Osaka University, Graduate School of Science,
  • 2003/04 - 2006/03 , Osaka University, Graduate School of Science,

Academic & Professional Experience

  • Apr. 2018 - Today , Kindai University Faculty of Biology-Oriented Science and Technology, Department of Genetic Engineering Lecturer
  • Jun. 2015 - Mar. 2018 , Harvard Medical School Department of Genetics Research Associate
  • Apr. 2015 - Mar. 2016 , Kindai University Institute of Advanced Technology Researcher
  • Aug. 2014 - Mar. 2015 , Tohoku University Institute of Development, Aging and Cancer Research Assistant Professor
  • Apr. 2006 - Jul. 2014 , Harvard Medical School Department of Genetics Research Fellow
  • Apr. 2007 - Mar. 2009 , Postdoctral Fellowship for Research Abroad Harvard Medical School
  • Apr. 2006 - Mar. 2007 , JSPS research fellow (PD) Harvard Medical School
  • Apr. 2005 - Mar. 2006 , JSPS research fellow (DC2) Osaka University

Research Activities

Research Areas

  • Life sciences, Genetics
  • Life sciences, Molecular biology
  • Life sciences, Cell biology
  • Life sciences, Genomics
  • Life sciences, Evolutionary biology
  • Life sciences, Developmental biology
  • Life sciences, Tumor biology

Research Interests

meiosis, meiotic recombination, Crossover control, Holliday junction, Holliday junction resolvase, structure specific endonuclease, Homologous recombination, Genomic instability, Progeroid syndromes, Bloom syndrome, Xeroderma pigmentosum, Fanconi anemia, DNA repair, Chromosome dynamics, Genomic integrity, mitosis, RNAi, P granule

Published Papers

  1. GRAS-1 is a novel regulator of early meiotic chromosome dynamics in C. elegans
    Marina Martinez-Garcia; Pedro Robles Naharro; Marnie W. Skinner; Kerstin A. Baran; Laura I. Lascarez-Lagunas; Saravanapriah Nadarajan; Nara Shin; Carlos G. Silva-García; Takamune T. Saito; Sara Beese-Sims; Brianna N. Diaz-Pacheco; Elizaveta Berson; Ana B. Castañer; Sarai Pacheco; Enrique Martinez-Perez; Philip W. Jordan; Monica P. Colaiácovo
    PLOS Genetics  19  (2)  , e1010666-e1010666, 21, Feb. 2023  , Refereed
  2. HIM-17 regulates the position of recombination events and GSP-1/2 localization to establish short arm identity on bivalents in meiosis
    Saravanapriah Nadarajan; Elisabeth Altendorfer; Takamune T. Saito; Marina Martinez-Garcia; Monica P. Colaiácovo
    Proceedings of the National Academy of Sciences  118  (17)  , e2016363118-e2016363118, 27, Apr. 2021  , Refereed
  3. The demethylase NMAD-1 regulates DNA replication and repair in the Caenorhabditis elegans germline.
    Simon Yuan Wang; Hui Mao; Hiroki Shibuya; Satoru Uzawa; Zach Klapholz O'Brown; Sage Wesenberg; Nara Shin; Takamune T Saito; Jinmin Gao; Barbara J Meyer; Monica P Colaiácovo; Eric Lieberman Greer
    PLoS genetics  15  (7)  , e1008252-, Jul. 2019  , Refereed

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Conference Activities & Talks

  1. Roles of structure specific endonucleases in larval development and meiosis , Koki Yamamoto; Takamune T. Saito , Kansai Worm Meeting , 8, Jan. 2023
  2. Relationship between unpaired chromosomes and crossover formation , Taiki Tsujiue; Takamune T. Saito , Kansai Aera Worm Meeting , 8, Jan. 2023
  3. Unpaired homologous chromosomes leads novel regulatory mechanisms of crossover formation in C. elegant meiosis. , Koki Yamamoto; Takamune T. Saito , 40th chromosome workshop , 21, Dec. 2022

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MISC

  1. 相同染色体間のギャップ形成が多様性を生む？ , 齋藤貴宗 , 実験医学 , 40 , 8 , 1276 , 1277 , May. 2022
  2. 分裂酵母の減数分裂特異的コイルドコイルタンパク質:Mcp4タンパク質の機能解析 , 大高彩美; 斉藤貴宗; 奥崎大介; 東岸任弘; 野島博 , 生化学 , 78 , 7 , 2006
  3. 分裂酵母Mek1は減数分裂前DNA合成の開始と相同組換えを制御する , 東岸任弘; 奥崎大介; 斉藤貴宗; 笠間隆志; 大高彩美; 野島博 , 日本分子生物学会年会プログラム・講演要旨集 , 27th , 2004

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Awards & Honors

  1. Dec. 2013, The Molecular Biology Society of Japan, The invitation plan for postdoctoral fellows from overseas
  2. May. 2011, Genetics Society of America, DeLill Nasser Awards
  3. Sep. 2010, Harvard Medical School, Postdoctoral Travel Awards

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Research Grants & Projects

  1. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Regulatory mechanisms of multinuclease complex , Kindai University
  2. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Novel machinery of maintenance of genomic integrity by multinuclease complexes , Kindai University
  3. Ministry of Education, Culture, Sports, Science and Technology, Grant-in-Aid for Young Scientists (B), Tissue-specific maintenance of genomic integrity by multinuclease complexes , 東北大学

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