Researchers

SADO Takashi

SADO Takashi
Professor
Faculty Department of Advanced Bioscience / Graduate School of Agriculture / Agricultural Technology and Innovation Research Institute
Researchmap https://researchmap.jp/read0079840

Education and Career

Education

  • Hokkaido University,
  • 1985/04 - 1989/03 , Hokkaido University, School of Science,
  • 1989/04 - 1995/06 , 北海道大学大学院理学研究科動物学専攻,

Academic & Professional Experience

  • Apr. 2014 - Today , Kindai University Faculty of Agriculture 教授
  • May. 2009 - Mar. 2014 , Medical Institute of Bioregulation, Kyushu Univ. Associate professor
  • Apr. 2000 - Apr. 2009 , The Graduate University for Advanced Studies
  • May. 1999 - Apr. 2009 , National Institute of Genetics

Research Activities

Research Areas

  • Life sciences, Genetics

Research Interests

クロマチン, ノンコーディングRNA, エピジェネティクス, X染色体不活性化, Epigenetics, DNA Methylation, X-inactivation

Published Papers

  1. Replication dynamics identifies the folding principles of the inactive X chromosome
    Rawin Poonperm; Saya Ichihara; Hisashi Miura; Akie Tanigawa; Koji Nagao; Chikashi Obuse; Takashi Sado; Ichiro Hiratani
    Nature Structural & Molecular Biology  30  (8)  , 1224-1237, 10, Aug. 2023  , Refereed
  2. SmcHD1 underlies the formation of H3K9me3 blocks on the inactive X chromosome in mice
    Saya Ichihara; Koji Nagao; Takehisa Sakaguchi; Chikashi Obuse; Takashi Sado
    Development  1, Aug. 2022  , Refereed
  3. Ectopic Splicing Disturbs the Function of Xist RNA to Establish the Stable Heterochromatin State
    Ruka Matsuura; Tatsuro Nakajima; Saya Ichihara; Takashi Sado
    Frontiers in Cell and Developmental Biology  9  14, Oct. 2021  , Refereed

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Books etc

  1. X-Chromosome Inactivation , Takashi Sado , Human Press (Springer Nature) , Sep. 2018
  2. Encyclopedia of Reproduction 2nd Edition , Takashi Sado , X-chromosome inactivation , X-chromosome inactivation , Academic Press (Elsevier) , Jul. 2018
  3. エピジェネティクス実験スタンダード , 中島達郎; 酒田祐佳; 佐渡 敬 , lncRNAの遺伝学的解析 , lncRNAの遺伝学的解析 , 羊土社 , May. 2017

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MISC

  1. Constitution of Higher Order Heterochromatin Structure Based on Epigenetic Code , Koji Nagao; Shin-Ya Isobe; Yoshi-Nobu Ohkubo; Yoko Hayashi-Takanaka; Hiroshi Kimura; Takashi Sado; Chikashi Obuse , GENES & GENETIC SYSTEMS , 91 , 6 , 318 , 318 , Dec. 2016
  2. X chromosome inactivation in the mouse , Takashi Sado , GENES & GENETIC SYSTEMS , 91 , 6 , 320 , 320 , Dec. 2016
  3. The defects in X-inactivation by partially dysfunctional Xist allele , Tatsuro Nakajima; Yuko Hoki; Hiroyuki Sasaki; Takashi Sado , GENES & GENETIC SYSTEMS , 90 , 6 , 390 , 390 , Dec. 2015

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Awards & Honors

  1. Sep. 2006, 日本遺伝学会, 奨励賞

Research Grants & Projects

  1. 日本学術振興会, 科学研究費助成事業 基盤研究(A), 生命発動と器官発生・制御に関わるヒト受精胚分子機序の解明 , 国立研究開発法人国立成育医療研究センター
  2. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (A), Elucidation of oocyte molecular mechanism on imprinted X chromosome inactivation enabling a sequential development , National Center for Child Health and Development
  3. 文部科学省, 科学研究費補助金 (新学術領域研究(研究領域提案型)), ヘテロクロマチン形成におけるXist RNA作動エレメントの役割

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