Researchers
- OUCHI Hidekazu
- Professor/Manager
| Faculty | Department of Pharmacy |
|---|---|
| Researchmap | https://researchmap.jp/read0185537 |
Education and Career
Education
- - 1990 , Tohoku Pharmaceutical University, Faculty of Pharmaceutical Science,
- - 1990 , 東北薬科大学, 薬学部,
- - 1995 , Tohoku Pharmaceutical University, Graduate School, Division of Pharmaceutical Sciences,
- - 1995 , 東北薬科大学, 薬学研究科,
Academic & Professional Experience
- Apr. 2013 - Today , Kinki University Faculty of Pharmacy Professor
- Apr. 2009 - Mar. 2013 , Aomori Univetsity Faculty of Pharmacy Professor
- Apr. 2007 - Mar. 2009 , Aomori Univetsity Faculty of Pharmacy Associate Professor
- Apr. 2006 - Mar. 2007 , Aomori Univetsity Faculty of Pharmacy Associate Professor
- Apr. 2005 - Mar. 2006 , Aomori Univetsity Faculty of Pharmacy Lecturer
- Feb. 2005 - Mar. 2005 , Tohoku Pharmaceutical University Faculty of Pharmacy Lecturer
- Apr. 1995 - Jan. 2005 , Tohoku Pharmaceutical University Faculty of Pharmacy Assistant Professor
Research Activities
Research Areas
- Life sciences, Pharmaceuticals - chemistry and drug development
Research Interests
薬学教育, 薬化学, 有機合成化学, Medicinal Chemistry, Heterocyclic Chemistry, Synthetic Organic Chemistry
Published Papers
-
The proposed structures of phenolic compounds isolated from Piper betle L. differ from those of the compounds obtained by total synthesis
Toshiro Noshita; Tatsuya Sato; Takahito Iwayama; Yohei Yamada; Hidekazu Ouchi
Natural Product Research 35 (21) , 3787-3793, 2, Nov. 2021 , Refereed -
Synthesis and biological activity of (±)-7,3′,4′-trihydroxyhomoisoflavan and its analogs
Toshiro Noshita; Kentaro Fujita; Takeru Koga; Hidekazu Ouchi; Akihiro Tai
Bioorganic & Medicinal Chemistry Letters 31 , 127674-127674, Jan. 2021 , Refereed -
Isolation and Identification of a Potent PTP1B Inhibitor, Ursolic Acid, from Carolina Jasmine (Gelsemium sempervirens (L.) J.St.-Hil.)
Toshiro Noshita; Yusuke Kakizoe; Satoshi Tanabe; Hidekazu Ouchi; Akihiro Tai
Letters in Organic Chemistry 17 (12) , 939-943, 8, Dec. 2020 , Refereed
Books etc
- コンプリヘンシブ基礎化学―有機・物化・分析・薬剤を学ぶために , 大内秀一 , 京都廣川書店 , Mar. 2016
- これからはじめるIT活用術 (薬剤師の強化書) , 大内秀一; 安藤裕明; 丁元鎮; 和田育男 , 構造式や反応式を簡単に書きたい , 構造式や反応式を簡単に書きたい , 南山堂 , Dec. 2009
MISC
- Hindsiilactone Aの合成研究 , 稲見俊伸; 野下俊朗; 大内秀一 , 日本農芸化学会中四国支部講演会講演要旨集(Web) , 42nd , C‐7 (WEB ONLY) , 13, Jun. 2015
- Hyper-responsibility of wide dynamic range (WDR) neurons in sural nerve ligation model of neuropathic pain and its suppression by gabapentin in mice , Y Omori; T Andoh; H Ouchi; H Takahata; H Nojima; Y Kuraishi , JOURNAL OF PHARMACOLOGICAL SCIENCES , 97 , 129P , 129P , 2005
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82(P-83) Synthesis and Inhibition of Glycosidases of D- and L-1-Deoxyazasugars
, Takahata Hiroki; Ouchi Hidekazu; Banba Yasunori; Kato Atsushi; Adachi Isao; Asano Naoki , 天然有機化合物討論会講演要旨集 , 46 , 467 , 472 , Oct. 2004
Summary:Azasugars (or iminosugars) are an important class of glycosidase inhibitors and are arousing great interest as potential therapeutic agents such as antidiabetics, antiobesities, antivirals, and therapeutic agents for some genetic disorders. Miglitol has been approved as the second-generation α-glucosidase inhibitor to treat type 2 diabetes and N-butyl-1-deoxynojirimycin has also been approved for use in patients with type 1 Gaucher disease in 2002 in the European Union and in 2003 in the U.S.A. Recently, it has been demonstrated that competitive inhibitors of lysosomal glycosidases have the...
Research Grants & Projects
- Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Development of a participatory learning support system connecting basic knowledge of pharmaceutical sciences to clinical , Kindai University
- Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Synthesis of C_2- symmetric α, α'-disubstituted azacycloalkanes as chiral building blocks and their application
- 日本学術振興会, 科学研究費助成事業, デオキシアザシュガー類の新規合成法の開発と生物活性評価 , 東北薬科大学