Researchers

OKADA Yoshiharu

OKADA Yoshiharu
Associate Professor
Faculty Department of Biotechnology and Chemistry / Graduate School of System Engineering
Researchmap https://researchmap.jp/9535

Education and Career

Education

  • - 1982 , Kyushu Institute of Technology, Faculty of Engineering,
  • - 1982 , Kyushu Institute of Technology, School of Engineering,

Academic & Professional Experience

  • Apr. 2013 - Today , Kindai University Faculty of Engineering, Department of Biotechnology and Chemistry 准教授
  • Apr. 2007 - Mar. 2013 , Kindai University Faculty of Engineering 准教授
  • Apr. 2003 - Mar. 2007 , Kindai University Faculty of Engineering 助教授
  • 1995 - 2003 , Kindai University Faculty of Engineering
  • 1993 - 1995 , Kyushu Institute of Technology
  • 1993 - 1995 , Kyushu Institute of Technology, Research
  • Assistant

Research Activities

Research Areas

  • Nanotechnology/Materials, Synthetic organic chemistry
  • Life sciences, Bioorganic chemistry
  • Nanotechnology/Materials, Structural/physical organic chemistry

Research Interests

有機合成, Asymmetric Synthesis

Published Papers

  1. Convenient Synthesis and Physiological Activities of Flavonoids in Coreopsis lanceolata L. Petals and Their Related Compounds
    OKADA Yoshiharu
    Molecules  23  (7)  , 1671-, Jul. 2018  , Refereed
  2. Relationship between the Oligosaccharide Content in Cooked Rice and Its Taste Characteristics
    横野一歩; 渡邉義之; 高津地志; 藤田明子; 岡田芳治; 野村正人
    Journal of the Japanese Society of Taste Technology  15  (2)  , 15-20, Jan. 2017  , Refereed
  3. Flavor Components in the Steam Generated during Rice Cooking and their Antioxidant Potential
    村上結城; 藤田明子; 渡邉義之; 岡田芳治; 野村正人
    Journal of the Japanese Society of Taste Technology  14  (1)  , 5-10, Jul. 2015  , Refereed

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Books etc

  1. リンの辞典 , 岡田 芳治 , 農薬 , 農薬 , 朝倉書店 , Nov. 2017

Conference Activities & Talks

  1. オオキンケイギク花弁中に含まれるフェニルプロパノイドの簡便合成 , 松永拓磨; 岡田芳治 , 日本化学会第104春季年会 , 18, Mar. 2024
  2. フラボノイドの簡便合成 , 松永拓磨; 岡田芳治 , 2023年日本化学会中国四国支部大会山口大会 , 11, Nov. 2023
  3. Canadensolideの合成研究 , 流出未那; 岡田芳治 , 日本化学会第103春季年会 , 23, Mar. 2023

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MISC

  1. MagnololおよびHonokiol配糖体の美肌効果に関する研究 , 澤邊 昭義; 山下 敦之; 竹田 竜嗣; 井上 俊夫; 石井 まや; 谷本 真一; 横野 一歩; 岡田 芳治; 野村 正人 , 日本栄養・食糧学会大会講演要旨集 , 71回 , 357 , 357 , Apr. 2017
  2. Studies on Cosmetic Whitening Effect and Antibacterial Activities of Dry Persimmon Peel (Diospyros Kaki THUNB.) , OKADA Yoshiharu; FUKAI Satomi; OTSUBO Eiji; NOMURA Masato , 近畿大学工学部研究報告 , 45 , 7 , 15 , 2011
    Summary:[SUMMARY] Persimmon peels (Diospyros Kaki THUNB.) are discarded during the production of dried fruit. The 2-methoxy-4-vinylphenol (8) which is component of persimmon peel had high antioxidant activity on the DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging assay and SOD (superoxide dismutase) assay. And (8) had higher tyrosinase inhibiting activity than that of arbutin using both L-tyrosine and L-DOPA as substrates. In addition, tyrosinase inhibitting activity of synthesized 2-methoxy-4-vinylphenol glycoside (12a) was studied. (12a) had tyrosinase inhibiting activity, suggesting that (12a) has possibilities for ingredient of cosmetics that are possessed of whitening effect. Moreover, for the creation of high value added product, we composed glycoside of (8) and cell toxicity assay with homosapiens origin alveolus epithelium cell strain A549 was carried on toward for these two kinds of compounds. Under high density condition (100 μg/mL), both of the compounds were not found to present toxic liability. Furthermore, we discovered that extracted hexane of dried persimmon include antibacterial activity (B. subtilis NBRC 3972, S. aureus NBRC13276 and E. coli NBRC3972) and ascertained methyl tridecanoate, 9-methyl hexadecenoate, 9-methyl octadecenoate, methyl tetradecanoate as the main components. Consequently we examined these components as the factor of antiseptic effect.
  3. Chemical constituents of YUZU and LIME essential oils and their antioxidative activities , Shinya Tachibana; Shinichi Tanimoto; Yoshihira Murai; Yoshiyuki Watanabe; Yoshiharu Okada; Masato Nomura , 近畿大学次世代基盤技術研究所報告 , 2 , 45 , 51 , 2011
    Summary:[Abstract] In this examination, antioxidant activities and whitening effects of yuzu(Citrus junos Sieb.ex Tanaka ) and lime(Citrus aurantifolia S.) essencial oils which are widely used in food flavors were studied. As a result, we found out that 1% to 2% concentration yuzu essencial oil contains equal antioxidant activity to □-tocopherol which is a substance commercially used as antioxidant. Also, from the result of tyrosinase activity inhibition test, an evaluation test on whitening effects, we found out that 1% to 2% concentration lime essencial oil contains higher inhibiting activation than arbutin which is a substance highly used in commercial cosmetics.

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Research Grants & Projects

  1. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Catalytic Asymmetric Synthesis of Physiologically Active Related compounds Bearing Lactone or Lactam Ring , Kinki University
  2. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, SYNTHESES OF NEW ORGANIC ELECTRON DONORS, ACCEPTORS, AND THEIR CHARGE-TRANSFER COMPLEXES, AND STUDIES ON THEIR PROPERTIES , KINKI UNIVERSITY
  3. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Development and Synthetic Application of a Novel Type of α-Phosphonocyclobutanones and α-Phosphonoazetidinones , Kinki University

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