Researchers
- NAKASHIMA Chisa
- Specially Appointed Associate Professor
Faculty | Department of Medicine |
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Researchmap | https://researchmap.jp/7000009573 |
Research Activities
Research Areas
- Life sciences, Dermatology
Published Papers
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Evaluation of the Accuracy of Artificial Intelligence (AI) Models in Dermatological Diagnosis and Comparison With Dermatology Specialists.
Yuto Yamamura; Kazuyasu Fujii; Chisa Nakashima; Atsushi Otsuka
Cureus 17 (1) , e77067-, Jan. 2025 -
TRPV1-positive sensory nerves and neuropeptides are involved in epidermal barrier repair after tape-stripping in mice
Kenji Usui; Chisa Nakashima; Sonoko Takahashi; Takaharu Okada; Yoshihiro Ishida; Saeko Nakajima; Akihiko Kitoh; Takashi Nomura; Teruki Dainichi; Tetsuya Honda; Rumi Katsumoto; Noriko Konishi; Mutsuyoshi Matsushita; Atsushi Otsuka; Kenji Kabashima
Journal of Allergy and Clinical Immunology Nov. 2023 -
Two cases of COVID-19 vaccine-related erythema multiforme under the administration of immune checkpoint inhibitors
Ayako Matsuo; Chisa Nakashima; Shigeto Yanagihara; Atsushi Otsuka
Trends in Immunotherapy 7 (2) , 2683-2683, 17, Oct. 2023
MISC
- 好酸球と好塩基球の活性化メカニズム 蕁麻疹の活動期に見られる好塩基球減少に関する動物モデルからの検証 , 岸本 泉; 馬 尼; 谷崎 英昭; 中嶋 千紗; 大塚 篤司; 三宅 健介; 烏山 一; 神戸 直智 , アレルギー , 70 , 6-7 , 799 , 799 , Aug. 2021
- Identification of CD49a+ CD8+ resident memory T cells in vitiligo-like lesions associated with nivolumab treatment for melanoma , C. Nakashima; Y. Ishida; K. Nakagawa; H. Irie; M. Hirata; T. Kataoka; A. Otsuka; K. Kabashima , Journal of the European Academy of Dermatology and Venereology , 34 , 2 , e79 , e82 , 1, Feb. 2020
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Skin Barrier Function and Atopic Dermatitis
, Pawinee Rerknimitr; Atsushi Otsuka; Chisa Nakashima; Kenji Kabashima , Current Dermatology Reports , 7 , 4 , 209 , 220 , 1, Dec. 2018
Summary:Purpose of Review: The purpose of this review was to highlight the importance of the skin barrier in the development of atopic dermatitis (AD). Recent Findings: Skin barrier function relies on the stratum corneum (SC) and tight junction. These components are deranged in the AD epidermis. Deficiency in filaggrin gives rise to abnormal epidermal integrity. The intercellular lipid composition, ratio, and organization are found to be disturbed. Keratinocyte shedding from the SC is also impaired. Tight junction proteins are reduced and result in sweat leakage into the skin surface. Summary: Strategies to enhance skin barrier strength will alleviate AD symptoms and may prevent the disease.
Research Grants & Projects
- 日本学術振興会, 科学研究費助成事業, アトピー性皮膚炎に対する新規治療の個別化医療のためのバイオマーカー探索 , 近畿大学
- Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Crosstalk between peripheral nerves and immune cells "To analyze the mechanism of skin pruritus" , Kyoto University
- Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, The crosstalk between peripheral nerves and immune cells in the pathogenesis of pruritic skin diseases. , Kyoto University