Researchers
- KUWAHARA Kazuhiko
- Associate Professor
Faculty | Department of Medicine |
---|---|
Researchmap | https://researchmap.jp/read0068817 |
Education and Career
Education
- 1983/04 - 1989/03 , Saga Medical School, 医学部,
- 1990/04 - 1994/03 , Saga Medical School, 大学院医学研究科,
Academic & Professional Experience
- Apr. 2025 - Today , Kindai University Faculty of Medicine Department of Pathology 准教授
- Apr. 2022 - Today , Kindai University Department of Diagnostic Pathology, Kindai University Hospital 講師
- Apr. 2021 - Mar. 2022 , Fujita Health University School of Medicine Department of Diagnostic Pathology 講師
- Apr. 2018 - Mar. 2021 , Fujita Health University School of Medicine Department of Diagnostic Pathology Assistant Professor
- Aug. 2016 - Mar. 2018 , Niigata University Graduate School of Medical and Dental Sciences 助教、講師
- Feb. 2016 - Jul. 2016 , Hirosaki University University Hospital 医員
- Apr. 2014 - Jan. 2016 , Aichi Cancer Center, Research Institute 腫瘍免疫学部 室長
- Apr. 1999 - Mar. 2014 , Kumamoto University, Faculty of Life Sciences, Department of Immunology Associate Professor
- Dec. 2001 - Mar. 2005 , 科学技術振興機構 さきがけ研究21 「認識と形成」領域 兼任研究者
- Jan. 1996 - Dec. 1998 , 日本学術振興会 特別研究員(PD)
- Apr. 1994 - Dec. 1995 , Tottori University School of Life Sciences, Faculty of Medicine 助手
- Jun. 1989 - Mar. 1990 , 佐賀医科大学 医学部附属病院 外科学 研修医
Research Activities
Research Areas
- Life sciences, Human pathology
Research Interests
抗体医薬, 転写共役型DNA傷害, 乳癌
Published Papers
-
Tumorigenesis Caused by Aberrant Expression of GANP, a Central Component in the Mammalian TREX-2 Complex—Lessons from Transcription-Coupled DNA Damages
Andri Rezano; Naomi Gondo; Yasuhiro Sakai; Yuko Nakamura; Suchada Phimsen; Tokio Tani; Akihiko Ito; Seiji Okada; Kazuhiko Kuwahara
International Journal of Molecular Sciences 19, Dec. 2024 -
Rare finding of mucorales sporangia and chlamydospores in tissue
Misa Kojima; Masatomo Kimura; Kazuhiko Kuwahara; Hisatomo Tamaki; Ryuji Yasumatsu; Sota Sadamoto; Takayuki Shinohara; Kazuki Amemiya; Yoshitsugu Miyazaki; Akihiko Ito
Pathology International Nov. 2024 -
Carcinogenesis caused by transcription‐coupled DNA damage through GANP and other components of the TREX‐2 complex
Yasuhiro Sakai; Kazuhiko Kuwahara
Pathology International Mar. 2024
Conference Activities & Talks
- The role of mammalian TREX2 complex in sporadic breast cancers. , Kazuhiko Kuwahara , The 3rd Bandung International Biomolecular Medicine Conference (BIBMC) , 2014
- DNA傷害の新たな視点 -mRNA輸送分子GANP欠損による転写共役型DNA損傷と発癌の実証- , 桑原 一彦 , 佐賀大学分子生命科学セミナー , 2012
- New Insights of transcription-coupled DNA damage in cell development and differentiation. , Kazuhiko Kuwahara , Special seminar in Department of Biochemistry, Faculty of Medicine, Khon Kaen University , 2011
MISC
- Molecular epidemiological studies of germinal center-associated nuclear protein (ganp) in the development of human sporadic breast cancers , Kazuhiko Kuwahara; Hidemi Ito; Kiyotaka Kuzushima; Hiroji Iwata; Hideo Tanaka; Keitaro Matsuo , CANCER RESEARCH , 76 , Jul. 2016
- DSS1 as potential prognostic marker for breast cancer progression and relapse-free patient survival , Andri Rezano; Kazuhiko Kuwahara; Mutsuko Yamamoto-Ibusuki; Masahiro Kitabatake; Penpak Moolthiya; Suchada Phimsen; Taiji Suda; Shigenobu Tone; Yutaka Yamamoto; Hirotaka Iwase; Nobuo Sakaguchi , INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE , 34 , S114 , S114 , 2014
- HIV-1 gp120/CD4&CXCR4膜融合複合体エピトープと感染阻止効果 , 戸田 哲平; 桑原 一彦; 近藤 直幸; 前田 洋助; 松田 善衛; 阪口 薫雄 , 日本エイズ学会誌 , 13 , 4 , 342 , 342 , Nov. 2011
Patents
- 胆管がん特異的糖鎖エピトープを認識するモノクローナル抗体 , 阪口薫雄, 桑原一彦, 荒木令江, 坂本珠美
- GANP蛋白質 , 阪口薫雄, 桑原一彦
- 高病原性トリインフルエンザに対する抗体 , 阪口薫雄, 桑原一彦, 小原道法, 芝崎太
Awards & Honors
- Nov. 2022, 日本病理学会, 学術研究賞演説(A演説)
- Oct. 2018, 藤田学園医学会, 産学連携推進センター長賞
- 2015, 愛知健康増進財団, 医学研究・健康増進活動等研究助成金
Research Grants & Projects
- Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), A novel strategy by PARP inhibitors for sporadic breast cancers , Fujita Health University
- 日本学術振興会, 科学研究費助成事業 挑戦的萌芽研究, TREX2複合体機能不全の誘導は抗がん剤感受性亢進の標的になるのか
- 日本学術振興会, 科学研究費助成事業 基盤研究(C), 非遺伝性散発性乳癌の発症、悪性進展におけるTREX2複合体因子の機能解析