Researchers

KUROSAKA Satoshi

KUROSAKA Satoshi
Associate Professor
Faculty Department of Genetic Engineering
Researchmap https://researchmap.jp/kurosaka

Education and Career

Education

  • 1991/04 - 1995/03 , Kyoto University, Faculty of Agriculture,
  • 1995/04 - 1997/03 , Kyoto University, Graduate School of Agriculture,
  • 1997/04 - 2002/03 , Kyoto University, Graduate School of Agriculture,

Academic & Professional Experience

  • Apr. 2023 - Today , Kindai University Institute of Advanced Technology Associate Professor
  • Apr. 2016 - Mar. 2023 , Kindai University Institute of Advanced Technology Lecturer
  • Apr. 2015 - Mar. 2016 , University of Pennsylvania School of Veterinary Medicine Visiting Scholar
  • Apr. 2013 - Mar. 2015 , RIKEN 脳科学総合研究センター 研究生
  • Oct. 2011 - Mar. 2015 , Hiroshima University 大学院医歯薬保健学研究科 特任助教
  • Oct. 2008 - Sep. 2011 , University of Pennsylvania School of Veterinary Medicine Research Associate
  • Nov. 2002 - Sep. 2008 , University of Pennsylvania School of Veterinary Medicine Postdoctoral Researcher
  • Apr. 2002 - Nov. 2002 , Kyoto University Graduate School of Agriculture 教務補佐員

Research Activities

Research Areas

  • Life sciences, Applied molecular and cellular biology
  • Life sciences, Animal production science
  • Life sciences, Developmental biology
  • Life sciences, Cell biology

Published Papers

  1. Species-specific formation of paraspeckles in intestinal epithelium revealed by characterization of NEAT1 in naked mole-rat.
    Akihiro Yamada; Hikaru Toya; Mayuko Tanahashi; Misuzu Kurihara; Mari Mito; Shintaro Iwasaki; Satoshi Kurosaka; Toru Takumi; Archa Fox; Yoshimi Kawamura; Kyoko Miura; Shinichi Nakagawa
    RNA (New York, N.Y.)  28  (8)  , 1128-1143, Aug. 2022  , Refereed
  2. Different translation dynamics of β- and γ-actin regulates cell migration.
    Pavan Vedula; Satoshi Kurosaka; Brittany MacTaggart; Qin Ni; Garegin Papoian; Yi Jiang; Dawei W Dong; Anna Kashina
    eLife  10  24, Jun. 2021  , Refereed
  3. Effects of exposure to methylglyoxal on sperm motility and embryonic development after fertilization in mice.
    Tatsuya Nakano; Mizuki Kono; Kazuki Segawa; Satoshi Kurosaka; Yoshiharu Nakaoka; Yoshiharu Morimoto; Tasuku Mitani
    The Journal of reproduction and development  67  (2)  , 123-133, 21, Apr. 2021  , Refereed

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Books etc

  1. 脳内環境 : 維持機構と破綻がもたらす疾患研究 , 高橋, 良輔 (臨床神経学); 漆谷, 真; 山中, 宏二; 樋口, 真人 , メディカルドゥ , Nov. 2014

MISC

  1. 受精卵におけるRNAPIIの転写制御機構の解明 , 高島さつき; 杉浦麻妃瑠; 山下幸軌; 中野志保; 松島秀斗; 清水奎伍; 黒坂哲; 中家雅隆; 三谷匡 , 日本分子生物学会年会プログラム・要旨集(Web) , 47th , 2024
  2. Establishment of iPS Cells and in vitro Production of Germ Cells in Wild Animal Species , Shimizu Kodai; Kurosaka Satoshi , 近畿大学先端技術総合研究所紀要 , 28 , 15 , 27 , 31, Mar. 2023
    Summary:Currently, many animal species on this planet are at risk of extinction, and the conservation of biodiversity is a pressing issue. The conservation program to maintain or recover the population of species outside their natural habitat by artificial reproduction at zoos, aquariums, etc, are called “ex situ conservation”. Establishment of pluripotent stem cells and in vitro production of germ cells have great potential to contribute to the successful ex situ conservation. Here, we introduce the history and current status of the establishment of iPS cells and in vitro production of germ cells in wild animal species, and discuss the future of ex situ conservation.
  3. 〈View〉Artificial Reproductive Techniques in Wild Animal Species , 黒坂哲; 安齋政幸 , Memoirs of Institute of Advanced Technology, Kindai University , 26 , 19 , 27 , 31, Mar. 2021
    Summary:[要旨]多くの生物種が絶滅の危機に瀕している現在、生物多様性を維持するための取り組みは急務である。その取り組みとして進められているのが生息地における生息数の確保を目的とした「域内保全」と動物園・水族館などにおける飼育下繁殖技術による「域外保全」である。いずれの場合も個体数と遺伝的多様性の双方の維持あるいは回復が求められており、域外保全においては可能な限り多くの個体に由来する生殖細胞を用いた人工繁殖技術の確立が必要である。本稿では、そのような技術の中で、1) 生殖細胞の保存および人工授精、2) 多能生幹細胞の樹立およびそれ由来の生殖細胞の作製、3) 性周期の予測および妊娠判定について述べる。[Abstract] Conservation of biodiversity is an urgent issue on this planet where many species face to extinction now. The conservation programs ongoing in animals are in situ conservation (conservation of ecosystems in the natural habitat to maintain or recover the population of species), and ex situ conservation (maintain or recover the population of species outside their natural habitat by artificial reproduction at zoos, aquariums, etc.). In both conservation programs, maintenance or recovery of population and genetic diversity are required, and the establishment of artificial reproduction using the germ cells from as many individuals as possible for successful ex situ conservation. Here, we introduce and discuss three potential reproductive techniques to achieve successful ex situ conservation, 1) germ cell preservation and artificial insemination, 2) in vitro production of germ cells, and 3) prediction of estrus and detection of pregnancy. Departmental Bulletin Paper application/pdf

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Research Grants & Projects

  1. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Study on protein degradation via N-end rule and arginylation in embryos acquiring totipotency. , Kindai University
  2. 日本学術振興会, 科学研究費助成事業 基盤研究(C), 初期胚のタンパク質分解におけるN末端則経路に関する研究 , 近畿大学
  3. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Basic research on resurrection by somatic cell nuclear transfer in ancient animals , Kindai University

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