Researchers

IKEDA Hiroko

IKEDA Hiroko
Lecturer
Faculty Department of Life Science
Researchmap https://researchmap.jp/hi-ikeda

Education and Career

Education

  • 2006/04 - 2010/03 , Kindai University, Faculty of Science and Engineering,
  • 2010/04 - 2012/03 , Gunma University Graduate School of Medicine, 医学系研究科,
  • 2012/04 - 2017/03 , Gunma University Graduate School of Medicine, 医学系研究科,

Academic & Professional Experience

  • Apr. 2025 - Today , Kindai University Faculty of Science and Engineering, Department of Life Science Lecture
  • Apr. 2020 - Mar. 2025 , Kindai University Faculty of Science and Engineering, Department of Life Science Assistant professor
  • Apr. 2017 - Mar. 2020 , Gunma University Initiative for Advanced Research International Open Laboratory (Dr. Held lab, Harvard Medical School / MGH) Postdoctoral researcher

Research Activities

Research Areas

  • Environmental science/Agricultural science, Environmental effects of radiation
  • Life sciences, Radiology

Research Interests

Cell biology, Bystander effect, Radiation biology

Published Papers

  1. Continuous fractionated irradiation with irradiation-free intervals enhances survival and clonogenicity in osteosarcoma MG-63 cells via adaptive DNA damage response
    Hiroko Ikeda; Yuka Amano; Koki Hara; Yuito Tanaka; Eiki Isa; Nanami Shimomura; Toshifumi Tsujiuchi
    Advances in Biological Regulation  98  , 101114-101114, Dec. 2025  , Refereed
  2. Synthesis and Cancer Cell Targeting of a Boron-Modified Heat-Stable Enterotoxin Analog for Boron Neutron Capture Therapy (BNCT)
    Sota Okazaki; Yoshihide Hattori; Nana Sakata; Masaya Goto; Sarino Kitayama; Hiroko Ikeda; Toshiki Takei; Shigeru Shimamoto; Yuji Hidaka
    Chemistry  7  (4)  , 111-111, 30, Jun. 2025  , Refereed
  3. Regulation of cellular responses to X-ray irradiation through the activation of lysophosphatidic acid (LPA) receptor-3 (LPA3) and LPA2 in osteosarcoma cells
    Hiroko Ikeda; Miwa Takai; Narumi Yashiro; Yuka Amano; Koki Hara; Mao Yamamoto; Toshifumi Tsujiuchi
    Pathology - Research and Practice  257  , 155293-155293, May. 2024  , Refereed

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Books etc

  1. 臨床放射線生物学の基礎 , Joiner, Michael; Kogel, Albert van der; 安藤, 興一; 高橋, 昭久; 中野, 隆史; 古澤, 佳也; 放射線医療国際協力推進機構 , 第24章 正常組織反応の生物学的応答修復:基本原理と落とし穴 , 第24章 正常組織反応の生物学的応答修復:基本原理と落とし穴 , 放射線医療国際協力推進機構 , Dec. 2022

Conference Activities & Talks

  1. Impact of radiosensitivity differences in cancer cells on acquired resistance induced by continuous fractionated X-ray irradiation , Hiroko Ikeda; Yuka Amano; Koki Hara; Toshifumi Tsujiuchi , The 68th Annual Meeting of the Japanese Radiation Research Society / The 6th Asian Congress of Radiation Research , 25, Oct. 2025
  2. Roles of LPA receptor signaling in enhancing malignant potential of lung cancer cells under hypoxic conditions , Moemi Tamura; Narumi Yashiro; Mao Yamamoto; Yuka Kusumoto; Shion Nagano; Hiroko Ikeda; Toshifumi Tsujiuchi , The 84th Annual Meeting of the Japanese Cancer Association , 27, Sep. 2025
  3. Regulation of cellular functions through activation of free fatty acid receptors (FFARs) in lung cancer cells , Shion Nagano; Mao Yamamoto; Narumi Yashiro; Yuka Kusumoto; Moemi Tamura; Hiroko Ikeda; Toshifumi Tsujiuchi , The 84th Annual Meeting of the Japanese Cancer Association , 27, Sep. 2025

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MISC

  1. 宇宙放射線と重力変化環境の複合影響 , 高橋 昭久; 池田 裕子; 吉田 由香里 , 生体の科学 , 69 , 2 , 152 , 156 , Apr. 2018
  2. Performance evaluation of new devices to synchronize heavy-ion or X-ray irradiation and simulated microgravity for space radiation research ~ Improvement of a control stage ~. , Takahashi A.; Ikeda H.; Souda H.; Puspitasari A.; Held KD; Hidema J.; Nikawa T.; Yoshida Y.; Kanai T. , The 31st International Symposium on Space Technology and Science (ISTS), proceeding (Theses ID: 2017-p-09) , Mar. 2017
  3. Analysis of Gamma-ray Induced Bystander Effect between Human Lung Normal and Cancer Cells , Ikeda H; Yokota Y; Funayama T; Takahashi A; Kanai T; Nakano T; Kobayashi Y , QST Takasaki Annual Report 2015 , 111 , Mar. 2017

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Awards & Honors

  1. Sep. 2017, Japanese Society for Biological Sciences in Space, Young Investigator Award
  2. Nov. 2012, Atomic Energy Society of Japan, Kanto-Koetsu Branch (11th Young Researcher’s Presentation and Discussion Meeting), Award for Emerging Technology

Research Grants & Projects

  1. 日本学術振興会, 科学研究費助成事業, 放射線の耐性獲得におけるLPA受容体の選択的活性化と制御メカニズム , 近畿大学
  2. 日本学術振興会, 科学研究費助成事業, LPA受容体シグナルを介するがん細胞の抗がん剤・放射線感受性調節機構の解明 , 近畿大学
  3. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Early-Career Scientists, Mechanism elucidation of bystander effects focusing on DNA repair in radioresistant chondrosarcoma cells , Kindai University