Researchers

IHARA Makoto

Faculty	Department of Applied Biological Chemistry / Graduate School of Agriculture
Researchmap	https://researchmap.jp/makoto.ihara

Apr. 2018 - Today , Kindai University Fuculty of agriculture Associate professor
Apr. 2013 - Mar. 2018 , Kinki University Faculty of Agriculture Lecturer
Dec. 2012 - Mar. 2018 , RIKEN SPring-8 Center Visiting Scientist
Dec. 2012 - Mar. 2013 , Okayama University, Graduate school of medicine, dentistry and pharmaceutical sciences Assistant Professor
Oct. 2006 - Nov. 2012 , RIKEN
Apr. 2005 - Sep. 2006 , 近畿大学研究員

Bioorganic chemistry, Pesticide science, 構造生理学, Structural Biology

Creating Pyrethrin Mimetic Phosphonates as Chemical Genetics Tools Targeting the GDSL Esterase/Lipase TcGLIP to Investigate Pyrethrin Biosynthesis
Noritada Matsuo; Yukimi Sugisaka; Shiori Aoyama; Makoto Ihara; Harue Shinoyama; Munetaka Hosokawa; Yoshinobu Kamakura; Daisuke Tanaka; Yoo Tanabe; Kazuhiko Matsuda
Journal of Medicinal Chemistry 66 (12) , 7959-7968, 13, Jun. 2023
Determinants of subtype-selectivity of the anthelmintic paraherquamide A on Caenorhabditis elegans nicotinic acetylcholine receptors.
Wataru Koizumi; Shuya Otsubo; Shogo Furutani; Kunihiro Niki; Koichi Takayama; Shota Fujimura; Takanobu Maekawa; Ryosuke Koyari; Makoto Ihara; Kenji Kai; Hideo Hayashi; Mohammad Shaokat Ali; Eriko Kage-Nakadai; David B Sattelle; Kazuhiko Matsuda
Molecular pharmacology 22, Mar. 2023
Functional impact of subunit composition and compensation on Drosophila melanogaster nicotinic receptors-targets of neonicotinoids.
Yuma Komori; Koichi Takayama; Naoki Okamoto; Masaki Kamiya; Wataru Koizumi; Makoto Ihara; Daitaro Misawa; Kotaro Kamiya; Yuto Yoshinari; Kazuki Seike; Shu Kondo; Hiromu Tanimoto; Ryusuke Niwa; David B Sattelle; Kazuhiko Matsuda
PLoS genetics 19 (2) , e1010522-, Feb. 2023

Actions of clothianidin and related neonicotinoids on recombinant and native nicotinic acetylcholine receptors. , Makoto Ihara , XXII International Congress of Entomology, Brisbane, Australia , 2004
Structure activity relationship of clothianinidin and its related compounds , Makoto Ihara , The third Pan-Pacific Conference on Pesticide Science, Hawaii, USA. , 2003
Variations in agonist and antagonist profiles for neonicotinoids on recombinant nicotinic acetylcholine receptors expressed in Xenopus oocytes , Makoto Ihara , 10th IUPAC International Congress on the Chemistry of Crop Protection, Basel, Switzerland. , 2002

ピレスリン生合成に関わる TcGLIP の機能および構造の解明（３）−阻害活性と阻害の様式− , 竹内孝幸; 明石拓也; 宇都宮麻衣; 伊原誠; 平竹潤; 松田一彦 , 日本農芸化学会2015年度大会 , Mar. 2015
ピレスリン生合成に関わる TcGLIP の機能および構造の解明（２）−ホスホン酸型反応機構依存的阻害剤の設計と合成− , 明石拓也; 竹内孝幸; 宇都宮麻衣; 伊原誠; 松田一彦; 平竹潤 , 日本農芸化学会2015年度大会 , Mar. 2015
Exon 3 Splicing and Mutagenesis Identify Residues Influencing Cell Surface Density of Heterologously Expressed Silkworm (Bombyx mori) Glutamate-Gated Chloride Channels (vol 86, pg 686, 2014) , S. Furutani; M. Ihara; Y. Nishino; M. Akamatsu; A. K. Jones; D. B. Sattelle; K. Matsuda , MOLECULAR PHARMACOLOGY , 87 , 1 , 141 , 141 , Jan. 2015

日本学術振興会, 科学研究費助成事業基盤研究(B), 選択的害虫防除に向けた種選択能を有したニコチン性受容体標的薬剤設計の分子基盤研究 , 近畿大学
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B), Elucidation of the molecular determinants of neonicotinoid toxicity , Kindai University
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Elucidation of molecular mechanism of pyrethrin biosynthesis by a GDSL lipase and its application to creation of insect resistant plants , Kinki University