Researchers

HIDAKA Yuji

HIDAKA Yuji: Professor

Faculty	Department of Life Science / Graduate School of Science and Engineering
Researchmap	https://researchmap.jp/hidaka_Read

Education and Career

Academic & Professional Experience

2011 - Today , Kindai University Faculty of Science and Engineering 教授

Research Activities

Research Areas

Life sciences, Biophysics
Nanotechnology/Materials, Molecular biochemistry
Life sciences, Structural biochemistry

Research Interests

bombyx mori, chemical biology, cocoonase, trypsin, protease, フォールディング, ウログアニリン, グアニル酸シクラーゼ, 結晶構造, 生理活性ペプチド, ペプチドホルモン, 前駆体, グアニリン, プロ領域, プロセッシング, 耐熱性エンテロトキシン, ナトリウム利尿ペプチド, ペプチドホルモン前駆体, 分子内シャペロン, プロペプチド

Published Papers

Synthesis and Cancer Cell Targeting of a Boron-Modified Heat-Stable Enterotoxin Analog for Boron Neutron Capture Therapy (BNCT)
Sota Okazaki; Yoshihide Hattori; ORCID,Nana Sakata; Masaya Goto; Sarino Kitayama; Hiroko Ikeda; Toshiki Takei; Shigeru Shimamoto; Yuji Hidaka
Chemistry 7 (4) , 111-, Jun. 2025 , Refereed
Mutational Analysis of Substrate Recognition in Trypsin-like Protease Cocoonase: Protein Memory Induced by Alterations in Substrate-Binding Site
Nana Sakata; Shigeru Shimamoto; Yuri Murakami; Orika Asida; Toshiki Takei; Mitsuhiro Miyazawa; Yuji Hidaka
Molecules 29 (22) , 5476-, 20, Nov. 2024 , Refereed
Mutational Analysis of the Substrate Binding Site of a Trypsin-like Serine Protease
Sakata, N.; Murakami, Y.; Ashida, O.; Miyazawa, M.; Shimamoto, S.; Hidaka, Y.; Sakata, N.; Murakami, Y.; Ashida, O.; Miyazawa, M.; Shimamoto, S.; Hidaka, Y.
Peptide Science 2023 , 165-168, Aug. 2024 , Refereed

トリプシン様酵素コクナーゼの基質認識部位の変異解析（優秀ポスター賞受賞） , 阪田菜奈; 村上友梨; 芦田織歌; 宮澤光博; 島本茂; 日髙雄二 , 第39 回関西地区ペプチドセミナー , 13, Dec. 2024
Mutational Analysis of the Substrate Binding Site of a Trypsin-like Serine Protease , akata, N.; Murakami, Y.; Ashida, O.; Miyazawa, M.; Shimamoto, S.; Hidaka, Y. , 第60回ペプチド討論会 , 9, Nov. 2024
Biological Activity of the Joining Peptide of Proopiomelanocortin , Hiroshima, K.; Sakata, N.; Konogami, T.; Shimamoto, S.; Hidaka, Y. , 第60回ペプチド討論会 , 9, Nov. 2023

Mechanism of the Disulfide-Coupled Folding of a de novo Designed Prouroguanylin Protein , Mayu Fukutsuji; Aman L. Maharjan; Toi Osumi; Shigeru Shimamoto; Yuji Hidaka , BIOPHYSICAL JOURNAL , 118 , 3 , 508A , 508A , Feb. 2020
Exploring Serum Proteins to Stabilize the Conformation of the Precursor Protein of ANP , Yuji Hidaka; Hayato Ueda; Shigeru Shimamoto , BIOPHYSICAL JOURNAL , 118 , 3 , 59A , 59A , Feb. 2020
Intra-Molecular Chaperone Mediated Folding of a Peptide Hormone in Molecular Evolution , Toi Osumi; Aman L. Maharjan; Mayu Fukutsuji; Shigeru Shimamoto; Yuji Hidaka , BIOPHYSICAL JOURNAL , 118 , 3 , 510A , 511A , Feb. 2020