Researchers

HAYASHI Hidetoshi

HAYASHI Hidetoshi
Professor/Senior Staff
Faculty Department of Medicine / Graduate School of Medical Sciences
Researchmap https://researchmap.jp/hayashi_h

Education and Career

Education

  • 1997/04 - 2003/03 , Osaka University, Faculty of Medicine,
  • 2009/04 - 2012/03 , Kindai University, Faculty of Medicine,

Academic & Professional Experience

  • Apr. 2023 - Today , Kindai University, Faculty of Medicine Department of Medical Oncology Professor
  • Apr. 2022 - Today , Kindai University, Faculty of Medicine Department of Medical Oncology 特命准教授
  • Apr. 2020 - Mar. 2022 , 近畿大学医学部 内科学腫瘍内科 講師
  • Oct. 2015 - Mar. 2020 , Kindai university hospital Department of Medical Oncology Lecturer
  • Apr. 2015 - Sep. 2015 , Kindai university hospital Department of Medical Oncology Assistant professor
  • Apr. 2013 - Mar. 2015 , Kishiwada City Hospital Department of Medical Oncology Director
  • Apr. 2009 - Mar. 2013 , Kindai university hospital Department of Medical Oncology assistant professor
  • Apr. 2006 - Mar. 2009 , Kurashiki Central Hospital Respiratory Medicine Medical Staff
  • Apr. 2003 - Mar. 2006 , Sumitomo Hospital General Medicine Resident

Research Activities

Research Areas

  • Life sciences, Tumor diagnostics and therapeutics

Research Interests

Cancer of Unknown Primary, Lung Cancer, Gene analysis, medical oncology, immune checkpoint inhibitor

Published Papers

  1. Soluble immune checkpoint factors reflect exhaustion of antitumor immunity and response to PD-1 blockade
    Hidetoshi Hayashi; Kenji Chamoto; Ryusuke Hatae; Takashi Kurosaki; Yosuke Togashi; Kazuya Fukuoka; Megumi Goto; Yasutaka Chiba; Shuta Tomida; Takayo Ota; Koji Haratani; Takayuki Takahama; Junko Tanizaki; Takeshi Yoshida; Tsutomu Iwasa; Kaoru Tanaka; Masayuki Takeda; Tomoko Hirano; Hironori Yoshida; Hiroaki Ozasa; Yuichi Sakamori; Kazuko Sakai; Keiko Higuchi; Hitoshi Uga; Chihiro Suminaka; Toyohiro Hirai; Kazuto Nishio; Kazuhiko Nakagawa; Tasuku Honjo
    Journal of Clinical Investigation  1, Apr. 2024 
  2. Association of immune-related adverse events with durvalumab efficacy after chemoradiotherapy in patients with unresectable Stage III non-small cell lung cancer.
    Koji Haratani; Atsushi Nakamura; Nobuaki Mamesaya; Kenji Sawa; Yoshimasa Shiraishi; Ryota Saito; Junko Tanizaki; Yosuke Tamura; Akito Hata; Kosuke Tsuruno; Tomohiro Sakamoto; Shunsuke Teraoka; Masahide Oki; Hiroshi Watanabe; Takaaki Tokito; Kenji Nagata; Takeshi Masuda; Yasushi Nakamura; Kazuko Sakai; Yasutaka Chiba; Akihiko Ito; Kazuto Nishio; Nobuyuki Yamamoto; Kazuhiko Nakagawa; Hidetoshi Hayashi
    British journal of cancer  22, Mar. 2024 
  3. Hemophagocytic lymphohistiocytosis induced by nivolumab/ipilimumab combination therapy: A case of lung adenocarcinoma that responded to early steroid pulse therapy.
    Satoru Hagiwara; Junko Tanizaki; Hidetoshi Hayashi; Yoriaki Komeda; Naoshi Nishida; Akihiro Yoshida; Tomoki Yamamoto; Takuya Matsubara; Masatoshi Kudo
    Cancer reports (Hoboken, N.J.)  , e1960-, 9, Jan. 2024 

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Conference Activities & Talks

  1. Prognostic impact of EMT-related genes on post-operative prognosis in hepatocellular carcinoma. , 永井 知行; 荒尾 徳三; 松本 和子; 藤田 至彦; 林 秀敏; 木村 英晴; 萩原 智; 櫻井 俊治; 上嶋 一臣; 土師 誠二; 工藤 正俊; 西尾 和人 , AACR 103rd Annual Meeting 2011 , Mar. 2012
  2. 進行肺腺癌を対象としたゲフィチニブ／S-1併用療法第１層臨床試験 , 清田 秀美; 岡本 勇; 田中 薫; 林 秀敏; 寺嶋応顕; 東 公一; 武田真幸; 米阪 仁雄; 藤阪 保仁; 鶴谷 純司; 宮﨑 昌樹; 佐藤 太郎; 倉田 宝保; 中川 和彦 , 第51回日本肺癌学会総会 , Nov. 2010
  3. 進行肺腺癌を対象としたゲフェチニブ／S-1 併用療法第１相臨床試験 , 清田 秀美; 岡本 勇; 谷﨑 潤子; 文田 壮一; 岡本 邦男; 牧村 ちひろ; 竹澤 健; 田中 薫; 林 秀敏; 岡本 渉; 寺嶋応顕; 東 公一; 金田裕靖; 武田真幸; 上田 眞也; 米阪 仁雄; 藤阪 保仁; 鶴谷 純司; 宮﨑 昌樹; 佐藤 太郎; 倉田 宝保; 中川 和彦 , 第92回日本肺癌学会関西支部会 , Jul. 2010

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MISC

  1. PTPRRを介したEGFR活性化に起因するKRASG12C阻害薬耐性の克服(Combating acquired resistance to KRAS inhibitors in NSCLC by targeting PTPRR-mediated activation of EGFR signaling) , 金村 宙昌; 竹原 俊幸; 小野寺 勇太; 寺村 岳士; 鈴木 慎一郎; 坂井 和子; 西尾 和人; 中川 和彦; 林 秀敏; 米阪 仁雄 , 日本癌学会総会記事 , 82回 , 422 , 422 , Sep. 2023
  2. Providing Anti-Lung Cancer Drug Therapy Based on Genetic Information by Comprehensive Genomic Profiling , 米阪仁雄; 稲垣千昌; 稲垣千昌; 高濱隆幸; 高濱隆幸; 白石直樹; 磯本晃佑; 金村宙昌; 鈴木慎一郎; 谷崎潤子; 田中薫; 林秀敏; 中川和彦 , 日本癌学会学術総会抄録集(Web) , 82nd , 2023
  3. ニボルマブ+イピリムマブ併用療法中に敗血症との鑑別を要する免疫関連下垂体炎を発症した肺腺癌の1例 , 村田修一; 谷崎潤子; 岩朝勤; 黒崎隆; 田中薫; 林秀敏; 中川和彦; 濱有一郎 , 肺癌(Web) , 63 , 3 , 2023

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Patents

  1. 免疫チェックポイント阻害剤の奏効性の判定を補助する方法、試薬キット、装置及びコンピュータプログラム , 本庶 佑, 茶本 健司, 林 秀敏, 中川 和彦, 後藤 恵, 宇賀 均
  2. 免疫チェックポイント阻害剤の奏効性の判定を補助する方法、試薬キット、装置及びコンピュータプログラム , 本庶 佑, 茶本 健司, 林 秀敏, 中川 和彦, 後藤 恵, 宇賀 均 , 特許第7251738号

Awards & Honors

  1. Dec. 2022, 日本肺癌学会, 篠井・河合賞
  2. Jul. 2015, 日本臨床腫瘍学会, 日本臨床腫瘍学会奨励賞
  3. Jun. 2008, 西日本がん研究機構, 西日本がん研究機構賞

Research Grants & Projects

  1. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Validation study of a model to estimate the primary organ of cancer of unknown primary , Kindai University
  2. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Analysis of the risk factors for the development and severity of immune-related adverse events by immune checkpoint inhibitors , Kindai University
  3. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Immune related gene-expression profiling for the combination of chemotherapy and PD-1/PD-L1 inhibition. , Kindai University

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