Researchers

HAYASAKA Haruko

Faculty	Department of Life Science / Graduate School of Science and Engineering
Researchmap	https://researchmap.jp/read0210106

血管内皮細胞, ケモカイン, リンパ節, 転写因子, 接着分子, リンパ球, 癌転移, 細胞分化, リンパ節転移, 乳癌, 免疫組織, 細胞遊走, GPCR, 細胞運動, 膜ラッフル, 内皮細胞分化, ケミカルバイオロジー, 癌, バイオテクノロジー, 細胞接着分子

Endogenous CCL21-Ser deficiency reduces B16–F10 melanoma growth by enhanced antitumor immunity
Ryonosuke Fujie; Kaoru Kurowarabe; Yuki Yamada; Kakeru Fujiwara; Hayato Nakatani; Kenta Tsutsumi; Ryota Hayashi; Hinami Kawahata; Megumi Miyamoto; Madoka Ozawa; Tomoya Katakai; Yousuke Takahama; Izumi Ohigashi; Haruko Hayasaka
Heliyon 9 (8) , e19215-e19215, Aug. 2023 , Refereed
CCL21‐Ser expression in melanoma cells recruits CCR7+ naïve T cells to tumor tissues and promotes tumor growth
Megumi Miyamoto; Yuki Kawato; Ryonosuke Fujie; Kaoru Kurowarabe; Kakeru Fujiwara; Reika Nobusawa; Ryota Hayashi; Kei Iida; Izumi Ohigashi; Haruko Hayasaka
Cancer Science 114 (9) , 3509-3522, 8, Jul. 2023 , Refereed
A CCR4 antagonist attenuates atopic dermatitis-like skin inflammation by inhibiting the recruitment and expansion of Th2 cells and Th17 cells.
Masako Sato; Kazuhiko Matsuo; Yoko Susami; Ayaka Yamashita; Haruko Hayasaka; Yuta Hara; Keiji Nishiwaki; Naoki Oiso; Akira Kawada; Atsushi Otsuka; Takashi Nakayama
International immunology 35 (9) , 437-446, 5, Jun. 2023 , Refereed

ロアットカラー基本免疫学 , Delves, Peter J.; Roitt, Ivan Maurice; Martin, Seamus J.; Burton, Dennis R.; 宮坂, 昌之 , 7章 , 7章 , 西村書店 , Sep. 2011
がん転移研究の実験手法 , 日本がん転移学会 , 癌細胞のリアルタイムケモタキシス観察法 , 癌細胞のリアルタイムケモタキシス観察法 , 金芳堂 , 1, Jul. 2008
癌転移のメカニズムがよくわかる肝転移のすべて , 門田, 守人; 松浦, 成昭 , ケモカインと癌転移 , ケモカインと癌転移 , 永井書店 , 1, Jan. 2006

フラボノイド代謝物による腸間膜リンパ節の免疫応答抑制 , 柳利咲; 四之宮紗菜; 室田佳恵子; 早坂晴子 , 第28回日本フードファクター学会学術総会 , Nov. 2023
Experimental strategy for multi-sample screening of CCR7 activating molecules , 杉本叶多; 西村仁志; 片山ともか; 岡村大治; 岡村大治; 早坂晴子 , 日本分子生物学会年会プログラム・要旨集(Web) , 2023
Immunosuppressive effects of flavonoid metabolites in mesenteric lymph nodes , 柳利咲; 四之宮紗菜; 室田佳恵子; 室田佳恵子; 早坂晴子 , 日本分子生物学会年会プログラム・要旨集(Web) , 2023

Real-time monitoring of B16 melanoma cell viability by the firefly luciferase-based bioluminescence , Hinako Nishizaswa; Kaoru Kurowarabe; Ryota Hayashi; Haruko Hayasaka , Science and Technology , 32 , 5 , 11 , May. 2021
哺乳動物細胞における可溶型リンフォトキシン受容体タンパク質の発現 , 早坂晴子 , Science and technology = 理工学総合研究所研究報告 / 近畿大学理工学総合研究所編 , 31 , 55 , 61 , Feb. 2020
Lymphocyte Recirculation , Masayuki Miyasaka; Erina Hata; Kazuo Tohya; Haruko Hayasaka , Encyclopedia of Immunobiology , 3 , 486 , 492 , 27, Apr. 2016
Summary:Lymphocyte recirculation refers to the continuous transport of large numbers of naïve lymphocytes between the blood and lymphatic systems. After naïve lymphocytes are produced in the thymus or bone marrow, they enter the blood, where they spend about 30min, before migrating to the lymphoid and nonlymphoid organs. Subsequently, they leave these tissues and migrate continuously between the lymphoid and nonlymphoid organs, using the blood vessels and lymphatic system as trafficking routes. The human body contains as many as 5×1011 lymphocytes, which travel through the blood each day. Naïve T lymphocytes and B lymphocytes enter the lymph nodes or Peyer's patches by selectively adhering to and transmigrating through the high endothelial venules.

Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Transcriptional regulation of angiogenesis and tissue differentiation in microenvironment , Kindai University
日本学術振興会, 科学研究費助成事業, 麻酔薬圧拮抗作用の実時間イメージング , 近畿大学
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Lymphatic transport of dietary flavonoids: elucidation of its driving force and physiological roles , Shimane University