Researchers

FUJIWARA Toshinobu

FUJIWARA Toshinobu
Professor/Manager
Faculty Department of Pharmacy / Graduate School of Medicine
Researchmap https://researchmap.jp/RNA_Biochem

Education and Career

Academic & Professional Experience

  • Apr. 2015 - Today , Graduate School of Pharmaceutical Sciences, Kindai University Laboratory of Biochemistry Professor
  • Apr. 2013 - Mar. 2015 , Graduate School of Pharmaceutical Sciences, Nagoya City University Laboratory of Hygienic Chemistry Professor
  • Apr. 2011 - Mar. 2013 , Microbial Chemistry Research Foundation Institute of Microbial Chemistry Principal Investigator
  • Apr. 2010 - Mar. 2011 , Organization of Advanced Science and Technology, Kobe Univ. Core Team Associate Professor
  • Apr. 2007 - Mar. 2010 , Graduate School of Engineering, Kobe Univ. Department of Chemical Science and Engineering Associate Professor
  • Oct. 2006 - Mar. 2010 , JST PREST Researcher
  • Feb. 2003 - Mar. 2007 , Graduate School of Science and Technology, Kobe Univ. Department of Biosystems Scinece Assistant Professor

Research Activities

Research Areas

  • Life sciences, Functional biochemistry
  • Life sciences, Molecular biology

Research Interests

RNA engineering, Analyses of RNA binding proteins, The initiation of mammalian protein synthesis, RNA ribosome translation

Published Papers

  1. TRBP modulates RLR signaling by inhibiting PKR-mediated antiviral stress granule formation.
    Koji Onomoto; Monami Sakai; Miyu Watanabe; Akira Fukao; Yurika Sakamura; Mai Miyao; Takumi Tomohiro; Akio Yamashita; Toshinobu Fujiwara; Tomoko Takahashi; Kumiko Ui-Tei; Mitsutoshi Yoneyama
    Scientific reports  15  (1)  , 20678-20678, 1, Jul. 2025 
  2. Starvation changes the pre-rRNA accumulations in Caenorhabditis elegans.
    Shahriar Rahman Shovon; Tomoki Uematsu; Yuki Osaki; Tatsushi Masui; Takashi Koyama; Toshinobu Fujiwara; Chisato Ushida
    Biochemical and biophysical research communications  742  , 151125-151125, Jan. 2025 
  3. Enhanced Broad-Spectrum Efficacy of an L2-Based mRNA Vaccine Targeting HPV Types 6, 11, 16, 18, with Cross-Protection Against Multiple Additional High-Risk Types.
    Kosuke Tsukamoto; Akio Yamashita; Masatoshi Maeki; Manabu Tokeshi; Hirotatsu Imai; Akira Fukao; Toshinobu Fujiwara; Koji Okudera; Nobuhisa Mizuki; Kenji Okuda; Masaru Shimada
    Vaccines  12  (11)  30, Oct. 2024 

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MISC

  1. Translation control mediated by stress granule related factors G3BP1/2 , 森あゆみ; 宮尾真衣; 友廣拓生; 深尾亜喜良; 足達俊吾; 夏目徹; 尾野本浩司; 米山光俊; 鈴木亨; 山本雅; 藤原俊伸 , 日本分子生物学会年会プログラム・要旨集(Web) , 46th , 2023
  2. Redefining miRISC-mediated translation regulation , 宮尾真衣; 森あゆみ; 坂村由梨佳; 友廣拓生; 深尾亜喜良; 船上仁範; 足達俊吾; 夏目徹; 尾野本浩司; 米山光俊; 鈴木亨; 山本雅; 藤原俊伸 , 日本分子生物学会年会プログラム・要旨集(Web) , 45th , 2022
  3. Analysis of translation regulation mechanisms by ARE-binding protein, AUF1 , 西阪皓理; 友廣拓生; 深尾亜喜良; 船上仁範; 藤原俊伸 , 日本分子生物学会年会プログラム・要旨集(Web) , 44th , 2021

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Awards & Honors

  1. Mar. 2014, 上原記念生命科学財団, 研究推進特別奨励賞
  2. Mar. 2012, 内藤記念科学振興財団, 若手ステップアップ研究奨励賞
  3. Apr. 2008, 長瀬科学技術振興財団, 振興賞

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Research Grants & Projects

  1. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Tissue-specific regulation of translation initiation mediated by ribosome heterogeneity , Kindai University
  2. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), A multidisciplinary approach to establish the structural basis of dosage compensation
  3. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Elucidation of the operation principle of the translation repression by microRNA machinery in human , Kindai University

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