Researchers
- FUJII Masayuki
- Professor
| Faculty | Department of Biological and Environmental Chemistry / Graduate School of Humanity-Oriented Science and Engineering |
|---|---|
| Researchmap | https://researchmap.jp/read0181541 |
Education and Career
Education
- 1979/04 - 1983/03 , Kyoto University, Faculty of Science,
- 1983/04 - 1985/03 , Kyoto University, Graduate School of Science,
- 1985/04 - 1987/03 , Kyoto University, Graduate School of Science,
Academic & Professional Experience
- Apr. 2002 - Today , Kindai University 九州工学部（現産業理工学部） Professor
- Apr. 1992 - Mar. 2002 , Kindai University 九州工学部（現産業理工学部） 准教授
- Apr. 1990 - Mar. 1992 , Kindai University 九州工学部（現産業理工学部） 講師
- Oct. 1987 - Mar. 1990 , Kindai University 九州工学部（現産業理工学部） 助手
- Apr. 1987 - Sep. 1987 , Kindai University 環境科学研究所 助手
Research Activities
Research Areas
- Life sciences, Pharmaceuticals - chemistry and drug development
- Life sciences, Bioorganic chemistry
- Nanotechnology/Materials, Structural/physical organic chemistry
- Nanotechnology/Materials, Molecular biochemistry
Research Interests
医薬分子機能学, 核酸化学, 有機合成化学, Molecular Pharmaceuticals, Nucleic Acid Chemistry, Synthetic Organic Chemistry
Published Papers
-
Elimination of Off-target Effect by Chemical Modification of 5’-End of siRNA
Yasuo Shiohama; Ryosuke Fujita; Maika Sonokawa; Masaaki Hisano; Yojiro Kotake; Marija Krstic-Demonacos; Constantinos Demonacos; Gengo Kashiwazaki; Takashi Kitayama; Masayuki Fujii
Nucleic Acid Therapeutics 32 (5) , 438-447, 14, Oct. 2022 , Refereed -
Quantitative PCR Discriminating Point Mutation of KRAS Gene Using Chemically Modified Primers
Ryosuke Fujita; Maika Sonokawa; Masaaki Hisano; Masayuki Fujii
Reports of Faculty of Humanity-Oriented Science and Engineering, Kindai University 33 , 43-48, 30, Jun. 2022 , Refereed -
Allele Specific Quantitative PCR Using Proofreading Polymerase
Ryosuke Fujita; Maika Sonokawa; Masaaki Hisano; Masayuki Fujii
Reports of Faculty of Humanity-Oriented Science and Engineering, Kindai University 33 , 49-56, 30, Jun. 2022 , Refereed
Books etc
- Handbook of Chemical Biology of Nucleic Acids , Masayuki Fujii; Marija Krstic-Demonacos; Constantinos Demonacos , Controlled Intracellular Trafficking and Gene Silencing by Oligonucleotide-Signal Peptide Conjugates. Section 8. Nucleic Acids Therapeutics, Chapter 6, 1-33 , Controlled Intracellular Trafficking and Gene Silencing by Oligonucleotide-Signal Peptide Conjugates. Section 8. Nucleic Acids Therapeutics, Chapter 6, 1-33 , Springer-Verlag GmbH , 12, Apr. 2023
- Handbook for Nucleic Acid Science , FUJII Masayuki , Peptide-Nucleic Acid Conjugates , Peptide-Nucleic Acid Conjugates , Kodansha Scientific, Inc , Jan. 2020
- 中分子医薬開発に資するペプチド・核酸・糖鎖の合成・高機能化技術 , 藤井 政幸 , 第9章 核酸コンジュゲートの合成 , 第9章 核酸コンジュゲートの合成 , シーエムシー出版 , Feb. 2018
Conference Activities & Talks
- A Novel Regulation Method of mRNA Using RNA Stem-Loop Motif , Yasuo Shiohama; Masayuki Fujii , The 50th International Symposium on Nucleic Acids Chemistry , 2, Nov. 2023
- Crosstalk between Chemical Biology and Structural Biology of RNA Interference , Masayuki Fujii , Advances in Noncanonical Nucleic Acids 2023 , 19, Oct. 2023
- A Nobel Allele Specific PCR Using Chemically Modified Primers , Kana Inoue; Daichi Yano; Ryosuke Fujita; Masayuki Fujii , Biomedical Analysis Symposium , 28, Jul. 2023
MISC
- Effect of 5’-Modification on the Asymmetry Recognition of siRNA and the Elimination of Off-Target Effect , 藤井政幸; 神武洋二郎; 塩浜康雄 , 日本薬学会年会要旨集(Web) , 143rd , 2023
- 核酸医薬によるKRAS(G12D)の選択的発現制御 , 藤井政幸; 神武洋二郎; 塩浜康雄 , 医療薬学フォーラム講演要旨集 , 31st , 2023
- Gapmer ASOおよびsiRNAによるKRAS遺伝子1塩基変異の識別 , 藤井政幸; 塩浜康雄 , 日本核酸医薬学会年会講演要旨集 , 5th , 2019
Patents
- Method for transfecting nucleic acid to cell and nucleic acid complex , FUJII Masayuki , 特許China Patent 2310709
- Method for transfecting nucleic acid to cell and nucleic acid complex , FUJII Masayuki , 特許EU2594638
- Method for transfecting nucleic acid to cell and nucleic acid complex , FUJII Masayuki , 特許US9,057,067
Awards & Honors
- Oct. 2013, 日本学術振興機構, 特別研究員等審査会専門委員および国際事業委員会書面審査員表彰
- Jul. 2008, 有機合成化学協会, 第45回化学関連支部合同九州大会ポスター賞
- 1996, 有機合成化学協会武田薬品工業研究企画賞
Research Grants & Projects
- Kindai University, 21世紀研究開発奨励金（共同研究）, Development of Highly Sensitive and Accurate Detection of Mutant Cancer Genes , 21世紀研究開発奨励金（共同研究）
- 公益財団法人 柿原科学技術研究財団, 令和４年度科学技術研究助成事業, 新型コロナウイルス変異株高感度検出法の開発 , 近畿大学
- Kindai University, 21世紀研究開発奨励金（共同研究）, Synthesis and application of Biologically Active Compounds by Chemoenzymatic Approach with combination of Click Chemistry and Enzymatic Reaction , Kindai University