Researchers

CHIBA Yasutaka

CHIBA Yasutaka
Associate Professor
Faculty Kindai University Hospital / Graduate School of Medical Sciences
Researchmap https://researchmap.jp/read0069849

Education and Career

Education

  • 京都大学大学院, 医学研究科,

Academic & Professional Experience

  • Apr. 2015 - Today , Kinki University Hospital Clinical Research Center Associate Professor
  • Apr. 2011 - Mar. 2015 , Kinki University School of Medicine Clinical Research Center Lecturer
  • Apr. 2008 - Mar. 2011 , Kinki University School of Medicine Environmental Medicine and Behavioral Science Assistant Professor
  • Mar. 2003 - Mar. 2008 , Kyoto University School of Public Health Department of Biostatistics Assistant Professor

Research Activities

Research Areas

  • Life sciences , Healthcare management, medical sociology
  • Life sciences , Hygiene and public health (non-laboratory)
  • Informatics , Statistical science

Research Interests

医療統計学, Epidemiology, Biostatistics

Published Papers

  1. Chromosomal Instability Is Associated with cGAS-STING Activation in EGFR-TKI Refractory Non-Small-Cell Lung Cancer
    Kimio Yonesaka; Takashi Kurosaki; Junko Tanizaki; Hisato Kawakami; Kaoru Tanaka; Osamu Maenishi; Shiki Takamura; Kazuko Sakai; Yasutaka Chiba; Takeshi Teramura; Hiroki Goto; Eri Otsuka; Hiroaki Okida; Masanori Funabashi; Yuuri Hashimoto; Kenji Hirotani; Yasuki Kamai; Takashi Kagari; Kazuto Nishio; Kazuhiro Kakimi; Hidetoshi Hayashi
    CELLS  14  (6)  17, Mar. 2025 
  2. Dual single‑nucleotide polymorphism biomarker combination for opioid selection to treat cancer pain.
    Yoshihiko Fujita; Hiromichi Matsuoka; Yasutaka Chiba; Junji Tsurutani; Takeshi Yoshida; Kiyohiro Sakai; Miki Nakura; Ryo Sakamoto; Chihiro Makimura; Yoichi Ohtake; Kaoru Tanaka; Hidetoshi Hayashi; Takayuki Takahama; Junko Tanizaki; Atsuko Koyama; Kazuto Nishio; Kazuhiko Nakagawa
    Molecular and clinical oncology  22  (2)  , 14-14, Feb. 2025 
  3. Evaluation of immune checkpoint inhibitor efficacy for solid tumors withCD274(PD-L1 gene) amplification identified by comprehensive genomic profiling: retrospective study based on a nationwide database
    Tomohiro Nakayama; Takayuki Takahama; Yasutaka Chiba; Naoki Shiraishi; Hisato Kawakami; Kimio Yonesaka; Kazuhiko Nakagawa; Hidetoshi Hayashi
    Journal for ImmunoTherapy of Cancer  12  (12)  Dec. 2024  , Refereed

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Books etc

  1. 「医療統計力」を鍛える! , 千葉 康敬 , 総合医学 , 2015

Conference Activities & Talks

  1. 結果変数が順序カテゴリカル変数のときのランダム化試験における因果効果のベイズ推測 , 千葉康敬 , 統計関連学会連合大会 , 10, Sep. 2020
  2. Inference of average causal effects in a randomized trial with a binary outcome , Chiba Y , The 2019 International Causal Inference Conference , May. 2019
  3. Bayesian inference of causal effects in randomized trials with a binary outcome , Chiba Y , The 29th International Biometric Conference , Jul. 2018

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MISC

  1. Final results of adjuvant nivolumab for hepatocellular carcinoma (HCC) after surgical resection (SR) or radiofrequency ablation (RFA) (NIVOLVE): A phase 2 prospective multicenter single-arm trial and exploratory biomarker analysis , Masatoshi Kudo; Kazuomi Ueshima; Shin Nakahira; Naoshi Nishida; Hiroshi Ida; Yasunori Minami; Takuya Nakai; Hiroshi Wada; Shoji Kubo; Kazuyoshi Ohkawa; Asahiro Morishita; Takeo Nomi; Koji Ishida; Shogo Kobayashi; Makoto Umeda; Masakatsu Tsurusaki; Yasutaka Chiba; Kenichi Yoshimura; Kazuko Sakai; Kazuto Nishio , JOURNAL OF CLINICAL ONCOLOGY , 40 , 4 , Feb. 2022
  2. Adjuvant nivolumab for hepatocellular carcinoma (HCC) after surgical resection (SR) or radiofrequency ablation (RFA) (NIVOLVE): A phase 2 prospective multicenter single-arm trial and exploratory biomarker analysis. , Masatoshi Kudo; Kazuomi Ueshima; Shin Nakahira; Naoshi Nishida; Hiroshi Ida; Yasunori Minami; Takuya Nakai; Hiroshi Wada; Shoji Kubo; Kazuyoshi Ohkawa; Asahiro Morishita; Takeo Nomi; Koji Ishida; Shogo Kobayashi; Makoto Umeda; Masakatsu Tsurusaki; Yasutaka Chiba; Kenichi Yoshimura; Kazuko Sakai; Kazuto Nishio , JOURNAL OF CLINICAL ONCOLOGY , 39 , 15 , May. 2021
  3. VALUE OF ADDITIONAL ENDOSCOPIC ULTRASONOGRAPHY FOR SURVEILLANCE AFTER SURGICAL REMOVAL OF INTRADUCTAL PAPILLARY MUCINOUS NEOPLASMS , KAMATA Ken; CHIBA Yasutaka; WATANABE Tomohiro; SAKURAI Toshiharu; NISHIDA Naoshi; CHIKUGO Takaaki; MATSUMOTO Ippei; TAKEYAMA Yoshifumi; KITANO Masayuki; KUDO Masatoshi; TAKENAKA Mamoru; MINAGA Kosuke; OMOTO Shunsuke; MIYATA Takeshi; YAMAO Kentaro; IMAI Hajime; NAKAI Atsushi; TANAKA Hidekazu , GASTROENTEROLOGICAL ENDOSCOPY , 61 , 4 , 417 , 426 , 2019
    Summary:<p>Background and Aim: This study evaluated the utility of endoscopic ultrasonography (EUS) combined with contrast-enhanced harmonic EUS (CH-EUS) for surveillance of the remnant pancreas after surgery for intraductal papillary mucinous neoplasm (IPMN).</p><p>Methods: This was a single-center, retrospective, descriptive study. A total of 134 consecutive patients who underwent surgical resection for IPMN between April 2009 and March 2015 were evaluated. Rates of recurrence and development of IPMN-concomitant pancreatic ductal adenocarcinoma (PDAC) during follow up were assessed. Clinical findings of patients with recurrence or development of PDAC were also evaluated.</p><p>Results: Of 134 resected IPMN 56 (41.8%) and 78 (58.2%) were classified as benign and malignant, respectively. Patients were followed up for a median of 29 months, 33 (24.6%) by both contrast-enhanced computed tomography (CE-CT) and EUS, and 101 (75.4%) by computed tomography (CT) alone. Thirteen patients (9.7%) showed tumor recurrence, five with intra-pancreatic recurrence and eight with extra-pancreatic metastases. An enhancing mural nodule within the dilated main pancreatic duct was successfully detected by EUS in one patient, but not by CE-CT. Two patients developed IPMN-concomitant PDAC during follow up. EUS combined with CH-EUS successfully detected small IPMN-concomitant PDAC in two patients, whereas these lesions were not detected by CT. CH-EUS was useful for better visualization of the margins of IPMN-concomitant PDAC in one of these two patients.</p><p>Conclusion: Endoscopic ultrasonography combined with CH-EUS may improve follow up of patients with resected IPMN.</p>

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Awards & Honors

  1. May. 2006, 日本計量生物学会, 奨励賞
  2. 近畿大学医学会賞, （2010年 - 2014年）

Research Grants & Projects

  1. 日本学術振興会, 科学研究費助成事業, 筋産生因子アイリシン低値はインスリン抵抗性と骨折リスクを高めるか－10年追跡研究 , 大阪医科薬科大学
  2. 文部科学省, 科学研究費補助金(基盤研究(C)), 因果推論の方法論に対応する正確な統計解析手法の開発
  3. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, The predictive ability of osteoporotic fractures for a risk of cardiovascular disease based on organ crosstalk :10-years follow-up of a cohort study for osteoporosis risk in men. , Osaka Medical College

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