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スタッフ紹介

細野 眞(ほそのまこと)

氏名 細野 眞(ほそのまこと)
出身大学 京都大学大学院
経歴 昭和60年京都大学医学部卒業、平成5年京都大学大学院医学研究科博士課程修了、平成5年ドイツ連邦共和国フンボルト財団奨学研究員(ボン大学)、平成6年フランス政府給費留学生(国立保険医学研究所)、平成7年埼玉医科大学講師、平成15年近畿大学助教授、平成17年近畿大学医学部放射線医学教室・高度先端総合医療センター教授、平成19年近畿大学原子力研究所教授兼務
学位 医学博士 
専門分野 放射線医学、核医学、腫瘍免疫学、放射線防護
担当授業科目  
研究テーマ (1)陽電子断層撮影による腫瘍の病態解明
(2)放射能標識化合物による腫瘍イメージング
(3)核医学治療(=RI内用療法、甲状腺疾患・骨転移・悪性リンパ腫)
(4)精神神経疾患における高次機能の解析
(5)医療における放射線防護
所属学会 日本放射線学会、日本核医学会、日本画像医学会、米国核医学会、フランス核医学会、ヨーロッパ核医学会
社会活動 国際原子力機関医療放射線運営委員会委員
文部科学省放射線審議会専門委員
日本アイソトープ協会理事・学術諮問委員、医学薬学部会委員
日本医学放射線学会代議員・学術研究委員会委員
日本核医学会理事・PET核医学委員会委員長
日本画像医学会評議員
断層映像研究会世話人
厚生労働科学研究補助金研究主任研究者
主要著書・論文 Tachibana I, Nishimura Y, Shibata T, Kanamori S, Nakamatsu K, Koike R, Nishikawa T, Ishikawa K, Tamura M, Hosono M. A Prospective Clinical Trial of Tumor Hypoxia Imaging with 18F-fluoromisonidazole Positron Emission Tomography and Computed Tomography (F-MISO PET/CT) before and during Radiation Therapy. J Radiation Research 2013;54(6):1078-84. doi: 10.1093/jrr/rrt033.
Sakaguchi K, Hosono M, Otsuka M, Hanaoka K, Usami K, Uto T, Ishii K. Dynamic sequence respiratory gated perfusion pulmonary SPECT without external tracking device. Ann Nucl Med 2013;27(1);65-73. doi: 10.1007/s12149-012-0658-4.
Tatsumi Y, Rai S, Shimada T, Yamaguchi K, Morita Y, Kawanishi K, Miyatake J, Ashida T, Hosono M, Matsumura I. Recognition of complete response by long-term observation after treatment with 90Y-Ibritumomab tiuxetan for relapsed follicular lymphoma. Acta Med Kinki Univ 2012;36(2):87-89.
Ishii K, Hanaoka K, Okada M, Kumano S, Komeya Y, Tsuchiya N, Hosono M, Murakami T. Impact of CT attenuation correction by SPECT/CT in brain perfusion images. Ann Nucl Med 2012;26(3):241-247.
Kakigi T, Hosono M, Taro Shimono T, Hiraoka T, Nishimura K. The iliac wing sign: an indicator of the presence of bone and/or soft-tissue injury of the pelvis and hips. European Journal of Radiology 2012;81:2348-2352.
Hanaoka K, Hosono M, Tatsumi Y, Komeya Y, Tsuchiya N, Usami K, Yuzuru Y, Ishii K, Sumita M. FDG uptake in bone marrow after G-CSF administration in patients with non-Hodgkin lymphoma. Nucl Med Commun 2011;Aug;32(8):678-683.
Hanaoka K, Hosono M, Shimono T, Usami K, Komeya Y, Tsuchiya N, Yamazoe Y, Ishii K, Tatsumi Y, Sumita M. Decreased brain FDG uptake in patients with extensive non-Hodgkin's lymphoma lesions. Ann Nucl Med 2010;24:707-711.
Okada M, Sato N, Ishii K, Matsumura K, Hosono M, Murakami T. FDG PET/CT versus CT, MR imaging, and 67Ga scintigraphy in the posttherapy evaluation of malignant lymphoma. Radiographics 2010;Jul-Aug;30(4):939-57.
Okubo M, Nishimura Y, Nakamatsu K, Okumura M, Shibata T, Kanamori S, Hanaoka K, Hosono M. Radiation treatment planning using positron emission and computed tomography for lung pharyngeal cancers: a multiple-threshold method for [18F]fluoro-2-deoxyglucose activity. Int J Radiation Oncology Biol Phys 2010;77:2:350-356.
Katsube T, Shimono T, Ashikaga R, Hosono M, Kitagaki H, Murakami T.
Demonstration of cerebellar atrophy in neuroacanthocytosis of 2 siblings.
Am J Neuroradiol 2009;30: 2: 386-8.
Okada M, Murakami T, Kumano S, Kuwabara M, Shimono T, Hosono M, Shiozaki H.
Integrated FDG-PET/CT compared with intravenous contrast enhanced CT for evaluation of metastatic regional lymph nodes in patients with resectable early stage esophageal cancer.
Ann Nucl Med 2009;23:1:73-80.
Shimono T, Hosono M, Ashikaga R et al.
Ring-shaped lateral ventricular nodules: an incidental finding on brain magnetic resonance imaging.
Neuroradiology 2009;51:3:145-150
Yoh T, Hosono M, Komeya Y et al.
Quantitative evaluation of norcholesterol scintigraphy, CT attenuation value, and chemical-shift MR imaging for characterizing adrenal adenomas.
Annals of Nuclear Medicine 2008;22:513-519.
Okubo M, Nishimura Y, Nakamatsu K, Okumura M, Shibata T, Kanamori S, Hanaoka K, Hosono M.
Static and moving phantom studies for radiation treatment planning in a positron emission tomography and computed tomography (PET/CT) system.
Ann Nucl Med 2008;22:579-586.
Kuwabara M, Shimono T, Toyomasu M, Shioyama M, Mitsui Y, Yoshinaga E, Kawada A, Hosono M, Murakami T, Kusunoki S.
Prominent ear sign on diffusion-weighted magnetic resonance imaging in relapsing polychondritis.
Radiat Med 2008;26:438-441.
Okada M, Murakami T, Kumano S, Imaoka I, Shimono T, Ashikaga R, Hosono M.
Comparison between one-route and two-routes injection for liver and aortic enhancement using multidetector computed tomography.
Am J Roentgenology 2008;190(6):323-326.
Shimono T, Tsuboyama T, Kuwabara M, Im SW, Yagyu Y, Imaoka I, Ashikaga R, Hosono M, Murakami T.
Discordance of motion artifacts on magnetic resonance imaging in Creutzfeldt-Jakob disease: comparison between diffusion-weighted and conventional imaging sequences.
Radiation Medicine 2008;26:151-155.
Hosono M.
Justification and optimization procedures for medical exposure.
World J of Nucl Med 2006;5:324-326
Hanada K, Hosono M,  Kudo T,  et al.
Regional cerebral blood flow in assessment of major depression and Alzheimer disease in the early elderly.
Nucl Med Commun 2006;27:535-541.
Takahashi T, Honda N, Hosono M, et al.
Aggressive multiple lung metastases from intracranial atypical meningioma.
Jpn J Tomography 2005;32(1):24-27.
Nakada H, Ishida H, Hashimoto D, Mori T, Hosono M.
Influence of different pneumoperitoneal pressures on tumor cell distribution in rats.
Surgical Endoscopy 2005;19(4):563-568
Mishra AK, Panwar P, Hosono M et al.
A new bifunctional chelating agent conjugated with monoclonal antibody and labelled with technetium-99m for targeted scintigraphy: 6- (4-isothiocyanatobenzyl) -5, 7-dioxo -1, 11- (carboxymethyl) -1, 4, 8, 11 - tetraazacyclotridecane.
J Drug Targeting 2004;12(9-10):559-567.
Takahashi T, Machida K, Honda N, Hosono M, et al.
Extraosseous accumulation of 99mTc-MDP in lymph node metastases of small cell carcinoma of the esophagus.
Ann Nucl Med 2004;18:157-160.
Honda N, Machida K, Matsumoto T, Matsuda H, Imabayashi E, Hashimoto J, Hosono M, et al.
Three-dimensional stereotactic surface projection of brain perfusion SPECT improves diagnosis of Alzheimer's disease.
Ann Nucl Med 2003;17:641-648.
Takahashi T, Machida K, Honda N, Hosono M, et al.
Effective radiotherapy and an abscopal effect for bone metastases of an unknown origin.
Japanese J Tomography 2003;30:96-99.
Ishida H, Nakada H, Takeuchi I, Yokoyama M, Okita T, Hashimoto D, Hosono M, et al.
Distribution of intrasplenically injected colon cancer cells following pneumoperitoneum in mice.
Surg Endosc 2003;17(8):1278-82
Takahashi T, Machida K, Honda N, Hosono M, et al.
Adult embryonal rhabdomyosarcoma in axilla.
Radiation Medicine 2003;21(3):135-137
Machida K, Inoue Y, Honda N, Hosono M, et al.
Spontaneous regression of chest wall malignant lymphoma presentation on Ga-67 imaging.
Clin Nucl Med 2003; 28 (5) :405-407
Hosono M, Machida K, Inoue Y, et al.
Gallium-67 demonstration of extensive soft-tissue involvement of multiple myeloma.
Ann Nucl Med 2003;17(1):69-72.
Hosono M, Machida K, Honda N, et al.
Visualization of fatal hepatic necrosis on bone scan.
Clinical Nuclear Medicine 2003;28(5):398-399
Hosono M, Machida K, Honda N, et al.
Intense gallium-67 accumulation in primary mediastinal pure seminomas.
Clinical Nuclear Medicine 2003;28(1):25-28.
受賞歴 医用原子力技術研究振興財団表彰(平成10年)、日本核医学会賞(平成21年)
趣味・その他 フランス語、生け花(小原流)
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