Drug Evaluation & Analysis

Research Project

Drug interaction studies based on apoptotic reactions induced by statins and fibrates.
Studies on improving cancer chemotherapy by limiting drug dosages.
Studies on the relationship between schizophrenia, i.e., Olanzapine, and metabolic syndrome.
Pharmacokinetic studies on tyrosine kinase inhibitors.
Studies on the evaluation of generic drugs.
Development of the new prodrug Quinolone to inhibit interaction (co-administration) with metal cations in gastrointestinal tract.

Introduction

In Japanese the word for drug is “kusuri.” The three syllables of the word “kusuri,” when reversed, become “ri-su-ku,” which translates into the word “risk” in English. This play on words represents the fact that with every drug there is a potential “risk.” The goal of our division is to determine the efficacy of drugs in order to minimize “risk.” Consequently, we employ the latest advances in pharmacokinetic theory and gene(tic) information to conduct research into effective methods for correct drug evaluation including (i) drug formulation; (ii) drug concentration and; (iii) gene status. In addition, our students (and post-doctoral colleagues) have access to many pharmaceutical science resources, as well as opportunities for both basic and applied research.