原子力研究所 スタッフ紹介

細野 眞

細野 眞(ほその まこと)
学位 医学博士
専門分野 放射線医学、核医学、腫瘍免疫学、放射線防護
担当授業科目
研究テーマ
1.
陽電子断層撮影による腫瘍の病態解明
2.
放射能標識化合物による腫瘍イメージング
3.
核医学治療(=RI内用療法、甲状腺疾患・骨転移・悪性リンパ腫)
4.
精神神経疾患における高次機能の解析
5.
医療における放射線防護
所属学会 日本放射線学会、日本核医学会、日本画像医学会、米国核医学会、フランス核医学会、ヨーロッパ核医学会
社会活動 国際原子力機関医療放射線運営委員会委員
文部科学省放射線審議会専門委員
日本アイソトープ協会理事・学術諮問委員、医学薬学部会委員
日本医学放射線学会代議員・学術研究委員会委員
日本核医学会理事・PET核医学委員会委員長
日本画像医学会評議員
断層映像研究会世話人
厚生労働科学研究補助金研究主任研究者
趣味・その他 フランス語、生け花(小原流)

学歴/経歴

出身大学

京都大学大学院

経歴

昭和60年京都大学医学部卒業、平成5年京都大学大学院医学研究科博士課程修了、平成5年ドイツ連邦共和国フンボルト財団奨学研究員(ボン大学)、平成6年フランス政府給費留学生(国立保険医学研究所)、平成7年埼玉医科大学講師、平成15年近畿大学助教授、平成17年近畿大学医学部放射線医学教室・高度先端総合医療センター教授、平成19年近畿大学原子力研究所教授兼務

研究活動情報

主要著書・論文

  1. Tachibana I, Nishimura Y, Shibata T, Kanamori S, Nakamatsu K, Koike R, Nishikawa T, Ishikawa K, Tamura M, Hosono M. A Prospective Clinical Trial of Tumor Hypoxia Imaging with 18F-fluoromisonidazole Positron Emission Tomography and Computed Tomography (F-MISO PET/CT) before and during Radiation Therapy. J Radiation Research 2013;54(6):1078-84. doi: 10.1093/jrr/rrt033.
  2. Sakaguchi K, Hosono M, Otsuka M, Hanaoka K, Usami K, Uto T, Ishii K. Dynamic sequence respiratory gated perfusion pulmonary SPECT without external tracking device. Ann Nucl Med 2013;27(1);65-73. doi: 10.1007/s12149-012-0658-4.
  3. Tatsumi Y, Rai S, Shimada T, Yamaguchi K, Morita Y, Kawanishi K, Miyatake J, Ashida T, Hosono M, Matsumura I. Recognition of complete response by long-term observation after treatment with 90Y-Ibritumomab tiuxetan for relapsed follicular lymphoma. Acta Med Kinki Univ 2012;36(2):87-89.
  4. Ishii K, Hanaoka K, Okada M, Kumano S, Komeya Y, Tsuchiya N, Hosono M, Murakami T. Impact of CT attenuation correction by SPECT/CT in brain perfusion images. Ann Nucl Med 2012;26(3):241-247.
  5. Kakigi T, Hosono M, Taro Shimono T, Hiraoka T, Nishimura K. The iliac wing sign: an indicator of the presence of bone and/or soft-tissue injury of the pelvis and hips. European Journal of Radiology 2012;81:2348-2352.
  6. Hanaoka K, Hosono M, Tatsumi Y, Komeya Y, Tsuchiya N, Usami K, Yuzuru Y, Ishii K, Sumita M. FDG uptake in bone marrow after G-CSF administration in patients with non-Hodgkin lymphoma. Nucl Med Commun 2011;Aug;32(8):678-683.
  7. Hanaoka K, Hosono M, Shimono T, Usami K, Komeya Y, Tsuchiya N, Yamazoe Y, Ishii K, Tatsumi Y, Sumita M. Decreased brain FDG uptake in patients with extensive non-Hodgkin's lymphoma lesions. Ann Nucl Med 2010;24:707-711.
  8. Okada M, Sato N, Ishii K, Matsumura K, Hosono M, Murakami T. FDG PET/CT versus CT, MR imaging, and 67Ga scintigraphy in the posttherapy evaluation of malignant lymphoma. Radiographics 2010;Jul-Aug;30(4):939-57.
  9. Okubo M, Nishimura Y, Nakamatsu K, Okumura M, Shibata T, Kanamori S, Hanaoka K, Hosono M. Radiation treatment planning using positron emission and computed tomography for lung pharyngeal cancers: a multiple-threshold method for [18F]fluoro-2-deoxyglucose activity. Int J Radiation Oncology Biol Phys 2010;77:2:350-356.
  10. Katsube T, Shimono T, Ashikaga R, Hosono M, Kitagaki H, Murakami T. Demonstration of cerebellar atrophy in neuroacanthocytosis of 2 siblings. Am J Neuroradiol 2009;30: 2: 386-8.
  11. Okada M, Murakami T, Kumano S, Kuwabara M, Shimono T, Hosono M, Shiozaki H. Integrated FDG-PET/CT compared with intravenous contrast enhanced CT for evaluation of metastatic regional lymph nodes in patients with resectable early stage esophageal cancer. Ann Nucl Med 2009;23:1:73-80.
  12. Shimono T, Hosono M, Ashikaga R et al. Ring-shaped lateral ventricular nodules: an incidental finding on brain magnetic resonance imaging. Neuroradiology 2009;51:3:145-150
  13. Yoh T, Hosono M, Komeya Y et al. Quantitative evaluation of norcholesterol scintigraphy, CT attenuation value, and chemical-shift MR imaging for characterizing adrenal adenomas. Annals of Nuclear Medicine 2008;22:513-519.
  14. Okubo M, Nishimura Y, Nakamatsu K, Okumura M, Shibata T, Kanamori S, Hanaoka K, Hosono M. Static and moving phantom studies for radiation treatment planning in a positron emission tomography and computed tomography (PET/CT) system. Ann Nucl Med 2008;22:579-586.
  15. Kuwabara M, Shimono T, Toyomasu M, Shioyama M, Mitsui Y, Yoshinaga E, Kawada A, Hosono M, Murakami T, Kusunoki S. Prominent ear sign on diffusion-weighted magnetic resonance imaging in relapsing polychondritis. Radiat Med 2008;26:438-441.
  16. Okada M, Murakami T, Kumano S, Imaoka I, Shimono T, Ashikaga R, Hosono M. Comparison between one-route and two-routes injection for liver and aortic enhancement using multidetector computed tomography. Am J Roentgenology 2008;190(6):323-326.
  17. Shimono T, Tsuboyama T, Kuwabara M, Im SW, Yagyu Y, Imaoka I, Ashikaga R, Hosono M, Murakami T. Discordance of motion artifacts on magnetic resonance imaging in Creutzfeldt-Jakob disease: comparison between diffusion-weighted and conventional imaging sequences. Radiation Medicine 2008;26:151-155.
  18. Hosono M. Justification and optimization procedures for medical exposure. World J of Nucl Med 2006;5:324-326
  19. Hanada K, Hosono M, Kudo T, et al. Regional cerebral blood flow in assessment of major depression and Alzheimer disease in the early elderly. Nucl Med Commun 2006;27:535-541.
  20. Takahashi T, Honda N, Hosono M, et al. Aggressive multiple lung metastases from intracranial atypical meningioma. Jpn J Tomography 2005;32(1):24-27.
  21. Nakada H, Ishida H, Hashimoto D, Mori T, Hosono M. Influence of different pneumoperitoneal pressures on tumor cell distribution in rats. Surgical Endoscopy 2005;19(4):563-568
  22. Mishra AK, Panwar P, Hosono M et al. A new bifunctional chelating agent conjugated with monoclonal antibody and labelled with technetium-99m for targeted scintigraphy: 6- (4-isothiocyanatobenzyl) -5, 7-dioxo -1, 11- (carboxymethyl) -1, 4, 8, 11 - tetraazacyclotridecane. J Drug Targeting 2004;12(9-10):559-567.
  23. Takahashi T, Machida K, Honda N, Hosono M, et al. Extraosseous accumulation of 99mTc-MDP in lymph node metastases of small cell carcinoma of the esophagus. Ann Nucl Med 2004;18:157-160.
  24. Honda N, Machida K, Matsumoto T, Matsuda H, Imabayashi E, Hashimoto J, Hosono M, et al. Three-dimensional stereotactic surface projection of brain perfusion SPECT improves diagnosis of Alzheimer's disease. Ann Nucl Med 2003;17:641-648.
  25. Takahashi T, Machida K, Honda N, Hosono M, et al. Effective radiotherapy and an abscopal effect for bone metastases of an unknown origin. Japanese J Tomography 2003;30:96-99.
  26. Ishida H, Nakada H, Takeuchi I, Yokoyama M, Okita T, Hashimoto D, Hosono M, et al. Distribution of intrasplenically injected colon cancer cells following pneumoperitoneum in mice. Surg Endosc 2003;17(8):1278-82
  27. Takahashi T, Machida K, Honda N, Hosono M, et al. Adult embryonal rhabdomyosarcoma in axilla. Radiation Medicine 2003;21(3):135-137
  28. Machida K, Inoue Y, Honda N, Hosono M, et al. Spontaneous regression of chest wall malignant lymphoma presentation on Ga-67 imaging. Clin Nucl Med 2003; 28 (5) :405-407
  29. Hosono M, Machida K, Inoue Y, et al. Gallium-67 demonstration of extensive soft-tissue involvement of multiple myeloma. Ann Nucl Med 2003;17(1):69-72.
  30. Hosono M, Machida K, Honda N, et al. Visualization of fatal hepatic necrosis on bone scan. Clinical Nuclear Medicine 2003;28(5):398-399
  31. Hosono M, Machida K, Honda N, et al. Intense gallium-67 accumulation in primary mediastinal pure seminomas. Clinical Nuclear Medicine 2003;28(1):25-28.

受賞歴

医用原子力技術研究振興財団表彰(平成10年)、日本核医学会賞(平成21年)

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