Reiko Sugiura
Faculty Department of Pharmaceutical Sciences / Graduate School of Medicine / Pharmaceutical Research and Technology Institute

Research Activities

Research Areas

  • Pharmacy, Biological pharmacy
  • Biological Science, Cell biology
  • Basic medicine, General pharmacology
  • Boundary agriculture, Applied molecular and cellular biology
  • Basic medicine, General pharmacology

Published Papers

  1. Distinct modes of stress granule assembly mediated by the KH-type RNA-binding protein Rnc1.
    Ryosuke Satoh, Nobuki Hara, Aki Kawasaki,Teruaki Takasaki, Reiko Sugiura
    Genes to Cells  23  (9)  , 778-785, Jul. 2018  , Refereed
  2. More than just an immunosuppressant: The emerging role of FTY720 as a novel inducer of ROS and apoptosis.
    Teruaki Takasaki, Kanako Hagihara, Ryosuke Satoh, Reiko Sugiura
    Oxid Med Cell Longev  2018  , 4397159-, Feb. 2018  , Refereed
  3. A genome-wide screen for FTY720-sensitive mutants reveals genes required for ROS homeostasis.
    Hagihara K, Kinoshita K, Ishida K, Hojo S, Kameoka Y, Satoh R, Takasaki T, Sugiura R
    Microbial cell (Graz, Austria)  4  (12)  , 390-401, Nov. 2017  , Refereed


Books etc

  1. Sourcebook of Models for Biomedical Research, Humana Press Inc., Molecular Genetic Approach to Identify Inhibitors of Signal Transduction Pathways. , Joint Work , 2008

Conference Activities & Talks

  1. A yeast-based phenotypic screen for ERK signaling modulators , Reiko Sugiura , German Japanese Workshop on Frontiers in Phosphatase Research and Drug Development , 22, Oct. 2018
  2. The Cutting Edge of Cancer Research -Approaching towards "Genome-based Drug Discovery" , Reiko Sugiura , 20, Aug. 2018
  3. Selective killing of cancer cells by ACA-28, a small molecule inducing ERK-dependent apoptosis: ~ A novel cancer therapy to stimulate oncogenic ERK signaling~ , Reiko Sugiura , 3, Jul. 2018



  1. The fission yeast pmk1+ gene encodes a novel mitogen-activated protein kinase homolog which regulates cell integrity and functions coordinately with the protein kinaseC pathway (Molecular and cellular biology - [16/,6752-6764]) , 1996
  2. Cloning and characterization of hsc1+, a heat shock cognate gene of the fission yeast Schizosa charomyces pombe (Gene - [181/,45-52]) , 1996
  3. Physiological Functions of PP2B(Calcineurin) (Cell Technology - [16/2,201-209]) , 1997



  1. Real time assay method for MAP kinase by monitoring of mRNA and exploiting new anti-cancer drug
  2. Analysis of interaction between nucleic acid and protein by affinity capillary electrophoresis
  3. Trainig kit and methods for anti-tumor cancer injection mixing

Research Grants & Projects

  1. Ministry of Education, Culture, Sports, Science and Technology, Grants-in-Aid for Scientific Research(新学術領域研究(研究領域提案型)), Regulatory mechanism of the cell integrity signaling mediated by mRNA-binding proteins , Reiko SUGIURA
  2. Ministry of Education, Culture, Sports, Science and Technology, Grants-in-Aid for Scientific Research(基盤研究(B)), Molecular Genetic Analysis of the MAPK Signaling Pathway , Reiko SUGIURA
  3. Ministry of Education, Culture, Sports, Science and Technology, Grants-in-Aid for Scientific Research(特定領域研究), Molecular genetic analysis of the RNA-mediated signaling pathways , Reiko SUGIURA