Academic Staff and Fellows
- KITAMATSU Mizuki
- Associate Professor Doctor of Engineering
- Department/Applied Chemistry Graduate school/Molecular and Material Engineering
This laboratory specializes in peptide chemistry and bio-organic chemistry. Our research efforts revolve around creating non-naturally occurring peptides and nucleic acids having new functions that are unavailable in natural peptides/proteins and nucleic acids.
A fragment peptide (B-9(66)) in trasncription factor p53 shows apoptotic activity.
Research Area | Chemical Biology, Peptide Chemistry |
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Teaching (Graduate Course) | Bio-Structural Materials Chemistry |
Research Interests | Drug delivery system, Cell-penetrating peptides, Bioactive peptides, Medicinal chemstry, Peptide nucleic acids |
Selected Publications |
(1) Reaction of Chloroacetyl-Modified Peptides with Mercaptoundecahydrododecaborate (BSH) Is Accelerated by Basic Amino Acid Residues in the Peptide Processes 2022, 10(11), 2200-2208, DOI:10.3390/pr10112200 (2) The SARS-CoV-2 Omicron BA.1 Spike G446S Mutation Potentiates Antiviral T Cell Recognition Nat. Commun. 2022, 13, 5440-5450, DOI:10.1038/s41467-022-33068-4 (3) Fluorescence Ratiometric DNA Detection by Peptide Nucleic Acid-Pyrene Binary Probes Bioorg. Med. Chem. Lett. 2022, 71, 128838-128841, DOI:10.1016/j.bmcl.2022.128838 |
Research and Achievements | |
Education (Undergraduate Course) |
Doshisha University |
Bio-Physical Chemistry Laboratory
kitamatu(at)apch.kindai.ac.jp
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Laboratory URL |
https://www.apch.kindai.ac.jp/laboratory/kitamatsu/index.html |